Protein: EIF3G
Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Translation initiation factor eIF3 p33 subunit) (eIF3 p33)

Gene: EIF3G, TIF35
Organism: Saccharomyces cerevisiae S288C
Interactions: 106
UniProt ID: Q04067

Gene Ontology (top 5):
GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0002188 - translation reinitiation
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005852 - eukaryotic translation initiation factor 3 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

438486

EIF3B
Eukaryotic translation initiation factor 3 subunit B

16

4

Small-scale

0.988

High

435341

RS3
Small ribosomal subunit protein uS3

3

3

Small-scale

0.827

High

821037

EIF3I
Eukaryotic translation initiation factor 3 subunit I

16

7

Small-scale

0.765

High

796625

EIF3A
Eukaryotic translation initiation factor 3 subunit A

12

4

Small-scale

0.756

High

738428

EIF3C
Eukaryotic translation initiation factor 3 subunit C

7

3

Small-scale

0.746

High

748197

SUI1
Eukaryotic translation initiation factor eIF-1

5

1

Small-scale

0.716

High

799768

IF5
Eukaryotic translation initiation factor 5

4

4

Small-scale

0.691

High

1044985

EIF3J
Eukaryotic translation initiation factor 3 subunit J

5

0

Small-scale

0.684

High

1044984

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

16

High-throughput

0.665

High

444616

DED1
ATP-dependent RNA helicase DED1

3

9

High-throughput

0.662

High

814035

IF2P
Eukaryotic translation initiation factor 5B

3

0

Small-scale

0.628

High

722233

XPO1
Exportin-1

1

11

High-throughput

0.618

High

836095

COPB2
Coatomer subunit beta'

1

4

High-throughput

0.618

High

1044995

DUF1
DUB-associated factor 1

1

11

High-throughput

0.618

High

403646

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

18

Small-scale

0.618

High

410325

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.618

High

464635

PBS2
MAP kinase kinase PBS2

1

12

High-throughput

0.618

High

819707

SSB2
Ribosome-associated molecular chaperone SSB2

3

2

High-throughput

0.611

High

737770

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

2

13

Small-scale

0.611

High

1041876

RLI1
Translation initiation factor RLI1

2

1

Small-scale

0.611

High

525046

HSP71
Heat shock protein SSA1

3

3

High-throughput

0.585

High

1039166

SYH1
SMY2 homolog 2

2

12

High-throughput

0.561

High

503226

RS22A
Small ribosomal subunit protein uS8A

2

1

High-throughput

0.558

High

689646

RS7A
Small ribosomal subunit protein eS7A

2

1

High-throughput

0.558

High

737942

HOG1
Mitogen-activated protein kinase HOG1

1

10

High-throughput

0.553

High

861047

RS10B
Small ribosomal subunit protein eS10B

1

1

High-throughput

0.536

High

923120

BRE5
UBP3-associated protein BRE5

1

16

High-throughput

0.536

High

393276

HSP82
ATP-dependent molecular chaperone HSP82

2

2

High-throughput

0.533

High

513206

RS8A
Small ribosomal subunit protein eS8A

2

2

High-throughput

0.533

High

802376

RS20
Small ribosomal subunit protein uS10

2

4

Small-scale

0.533

High

1043591

CLU
Clustered mitochondria protein 1

1

1

Small-scale

0.527

High

647210

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.517

High

671086

SIS1
Protein SIS1

1

2

High-throughput

0.515

High

792232

GBLP
Small ribosomal subunit protein RACK1

1

9

High-throughput

0.514

High

553653

ERF1
Eukaryotic peptide chain release factor subunit 1

1

1

Small-scale

0.501

High

655512

RS3A2
Small ribosomal subunit protein eS1B

1

1

High-throughput

0.489

High

688942

RS5
Small ribosomal subunit protein uS7

1

2

High-throughput

0.489

High

1030569

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

8

High-throughput

0.489

High

1044994

RS22B
Small ribosomal subunit protein uS8B

1

1

High-throughput

0.489

High

1044992

GLE1
mRNA export factor GLE1

1

6

Small-scale

0.481

High

757671

IF4B
Eukaryotic translation initiation factor 4B

1

2

Small-scale

0.481

High

430917

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

10

Small-scale

0.479

High

433837

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

438769

SC160
Protein SCP160

1

20

High-throughput

0.479

High

689128

RL16A
Large ribosomal subunit protein uL13A

1

3

High-throughput

0.479

High

923871

GIS2
Zinc finger protein GIS2

1

4

High-throughput

0.479

High

1033549

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

1044989

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

1044993

DBP10
ATP-dependent RNA helicase DBP10

1

11

High-throughput

0.479

High

796463

SLT11
Pre-mRNA-splicing factor SLT11

1

2

High-throughput

0.470

High

455247

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

558858

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

657126

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

Small-scale

0.458

High

778520

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

592486

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.445

High

812017

RS14B
Small ribosomal subunit protein uS11B

1

1

High-throughput

0.445

High

149944

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.437

High

382317

H4
Histone H4

1

2

High-throughput

0.437

High

436158

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.437

High

436509

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

5

High-throughput

0.437

High

442099

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

504403

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

512636

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

513909

RS11B
Small ribosomal subunit protein uS17B

1

2

High-throughput

0.437

High

514824

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.437

High

674822

RS2
Small ribosomal subunit protein uS5

1

2

Small-scale

0.437

High

753571

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

779341

CENPA
Histone H3-like centromeric protein CSE4

1

3

High-throughput

0.437

High

795521

ATG8
Autophagy-related protein 8

1

20

High-throughput

0.437

High

812626

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

824942

TM108
Protein TMA108

1

1

High-throughput

0.437

High

925384

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.437

High

963697

H3
Histone H3

1

3

High-throughput

0.437

High

1042222

TOM1
E3 ubiquitin-protein ligase TOM1

1

11

High-throughput

0.437

High

1044990

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.437

High

365179

KPYK1
Pyruvate kinase 1

1

2

High-throughput

0.407

High

453778

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.407

High

511853

RS24A
Small ribosomal subunit protein eS24A

1

1

High-throughput

0.407

High

527595

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.407

High

577209

SEC63
Protein translocation protein SEC63

1

3

High-throughput

0.407

High

626877

HSP60
Heat shock protein 60, mitochondrial

1

2

High-throughput

0.407

High

671700

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

676316

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.407

High

755167

GCN1
eIF-2-alpha kinase activator GCN1

1

10

High-throughput

0.407

High

811157

TCPZ
T-complex protein 1 subunit zeta

1

1

High-throughput

0.407

High

858062

RSSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.407

High

708086

TF2B
Transcription initiation factor IIB

3

0

High-throughput

0.335

High

383883

RS17A
Small ribosomal subunit protein eS17A

2

0

High-throughput

0.318

High

807782

CSK2C
Casein kinase II subunit beta'

2

0

High-throughput

0.307

High

817462

TDA2
Topoisomerase I damage affected protein 2

1

0

High-throughput

0.269

Low

849874

GNA1
Glucosamine 6-phosphate N-acetyltransferase

1

0

High-throughput

0.265

Low

745497

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.249

Low

782181

LAS1
Protein LAS1

1

0

Small-scale

0.249

Low

795195

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

825301

MOB1
DBF2 kinase activator protein MOB1

1

0

High-throughput

0.249

Low

826802

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

874514

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

1044724

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

1044986

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

1044987

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

1044988

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

368192

THDH
Threonine dehydratase, mitochondrial

1

0

High-throughput

0.232

Low

752691

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

812259

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.232

Low

1044991

MDN1
Midasin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025