HitPredict - High confidence protein-protein interactions

Protein: GRN
Progranulin (PGRN) (Acrogranin) (Epithelin/granulin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7]

Gene: GRN
Organism: Mus musculus
Interactions: 9
UniProt ID: P28798

Gene Ontology (top 5):
GO:0001834 - trophectodermal cell proliferation
GO:0001835 - blastocyst hatching
GO:0002265 - astrocyte activation involved in immune response
GO:0002282 - microglial cell activation involved in immune response
GO:0005125 - cytokine activity

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
705241	SLPI Antileukoproteinase	1	2	Small-scale	0.506	High
669441	TNR1B Tumor necrosis factor receptor superfamily member 1B	1	3	Small-scale	0.479	High
705243	SAP Prosaposin	1	2	High-throughput	0.479	High
705245	TLR9 Toll-like receptor 9	1	0	Small-scale	0.458	High
705244	BICD1 Protein bicaudal D homolog 1	1	1	High-throughput	0.445	High
663059	GRIA2 Glutamate receptor 2	1	0	Small-scale	0.426	High
705242	PTHD1 Patched domain-containing protein 1	1	0	Small-scale	0.426	High
705246	KCNQ2 Potassium voltage-gated channel subfamily KQT member 2	1	0	Small-scale	0.426	High
660916	IRF8 Interferon regulatory factor 8	1	0	High-throughput	0.249	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025