Protein: TLR9
Toll-like receptor 9 (CD antigen CD289)

Gene: TLR9
Organism: Mus musculus
Interactions: 24
UniProt ID: Q9EQU3

Gene Ontology (top 5):
GO:0001774 - microglial cell activation
GO:0001819 - positive regulation of cytokine production
GO:0002218 - activation of innate immune response
GO:0002237 - response to molecule of bacterial origin
GO:0002639 - positive regulation of immunoglobulin production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

431369

SRC
Proto-oncogene tyrosine-protein kinase Src

1

12

Small-scale

0.618

High

533125

CD14
Monocyte differentiation antigen CD14

1

20

Small-scale

0.618

High

945955

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

2

Small-scale

0.618

High

1040013

KPCZ
Protein kinase C zeta type

1

6

Small-scale

0.618

High

1222736

RASH
GTPase HRas

1

7

Small-scale

0.618

High

1224131

IRAK1
Interleukin-1 receptor-associated kinase 1

1

20

Small-scale

0.618

High

1424386

TLR9
Toll-like receptor 9

1

17

Small-scale

0.618

High

648078

MYD88
Myeloid differentiation primary response protein MyD88

2

20

Small-scale

0.586

High

1353894

UN93B
Protein unc-93 homolog B1

2

7

Small-scale

0.584

High

604530

SPI1
Transcription factor PU.1

1

5

Small-scale

0.534

High

237248

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

3

Small-scale

0.479

High

370863

FOS
Protein c-Fos

1

2

Small-scale

0.479

High

432103

JUN
Transcription factor Jun

1

1

Small-scale

0.479

High

465828

ENPL
Endoplasmin

1

4

Small-scale

0.479

High

583155

IRF1
Interferon regulatory factor 1

1

13

Small-scale

0.479

High

661096

IRF8
Interferon regulatory factor 8

1

13

High-throughput

0.479

High

663333

IRF2
Interferon regulatory factor 2

1

13

Small-scale

0.479

High

991157

HMGB1
High mobility group protein B1

1

6

Small-scale

0.479

High

999888

TRAF6
TNF receptor-associated factor 6

1

11

Small-scale

0.479

High

1424387

CHIP
E3 ubiquitin-protein ligase CHIP

1

6

Small-scale

0.479

High

705245

GRN
Progranulin

1

0

Small-scale

0.458

High

1282633

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.458

High

989286

HSP7C
Heat shock cognate 71 kDa protein

1

6

Small-scale

0.437

High


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Last updated: 11Aug2025