HitPredict
Protein: GUC2C
Guanylyl cyclase C (GC-C) (EC 4.6.1.2) (Heat-stable enterotoxin receptor) (STA receptor) (hSTAR) (Intestinal guanylate cyclase)

Gene: GUC2C, GUCY2C
Organism: Homo sapiens
Interactions: 4
UniProt ID: P25092

Gene Ontology (top 5):
GO:0001653 - peptide receptor activity
GO:0004383 - guanylate cyclase activity
GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0005525 - GTP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

669092

 NHRF4
Na(+)/H(+) exchange regulatory cofactor NHE-RF4

1

11

Small-scale

 0.586

High

669091

 NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

1

11

Small-scale

 0.501

High

669090

 GPC3
Glypican-3

1

1

High-throughput

 0.445

High

669093

 ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

 0.279

Low

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Last updated: 11Aug2025