HitPredict

Interactor 1: RNF4 (P78317)
E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (Small nuclear ring finger protein) (Protein SNURF)
Gene: RNF4

Interactor 2: TMX1 (Q9H3N1)
Thioredoxin-related transmembrane protein 1 (Protein disulfide-isomerase TMX1) (EC 5.3.4.1) (Thioredoxin domain-containing protein 1) (Transmembrane Trx-related protein)
Gene: TMX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29180619
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 190 Hs			1 280
+	Hs
		1005088 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		TMX4_HUMAN (20-261): 3.22e-53: 178: 41.98
+	Hs
		1004975 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		TMX3_HUMAN (6-270): 2.39e-44: 157: 15.94
+	Hs
		1004590 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		PDIA6_HUMAN (25-146): 2.92e-34: 130: 31.01
+	Hs
		1004838 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		TXND5_HUMAN (24-135): 7.67e-33: 126: 25.86
+	Hs
		566626 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		PDIA4_HUMAN (119-266): 1.21e-16: 81.3: 9.68
+	Hs
		717436 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		PDIA3_HUMAN (147-269): 6.26e-15: 76.3: 11.29
+	Hs
		1004799 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		DJC10_HUMAN (75-264): 9.7e-14: 72.9: 10.53
+	Hs
		452232 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		PDIA1_HUMAN (66-256): 3.31e-10: 62.1: 10.68
+	Hs
		1217886 BRE1A_HUMAN (13-190): 4.96e-24: 100: 18.82		TXND5_HUMAN (24-135): 7.67e-33: 126: 25.86