HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: PTK6 (Q13882)
Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)
Gene: PTK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 451
+	Hs
		440697 TCPH_HUMAN (4-532): 0: 591: 34.08		FYN_HUMAN (10-450): 0: 520: 42.79
+	Hs
		440187 TCPH_HUMAN (4-532): 0: 591: 34.08		LCK_HUMAN (3-449): 0: 517: 39.07
+	Hs
		440488 TCPB_HUMAN (1-535): 0: 586: 100.00		FYN_HUMAN (10-450): 0: 520: 42.79
+	Hs
		463055 TCPB_HUMAN (1-535): 0: 586: 100.00		YES_HUMAN (10-450): 0: 519: 42.86
+	Hs
		440024 TCPB_HUMAN (1-535): 0: 586: 100.00		LCK_HUMAN (3-449): 0: 517: 39.07
+	Hs
		486707 TCPH_HUMAN (4-532): 0: 591: 34.08		FGR_HUMAN (10-450): 3.39e-177: 508: 42.41
+	Hs
		1118420 TCPH_HUMAN (4-532): 0: 591: 34.08		PTK6_HUMAN (1-451): 1.75e-176: 503: 100.00
+	Hs
		486683 TCPB_HUMAN (1-535): 0: 586: 100.00		FGR_HUMAN (10-450): 3.39e-177: 508: 42.41
+	Hs
		440443 TCPG_HUMAN (3-532): 0: 561: 28.33		FYN_HUMAN (10-450): 0: 520: 42.79
+	Hs
		463025 TCPG_HUMAN (3-532): 0: 561: 28.33		YES_HUMAN (10-450): 0: 519: 42.86
+	Hs
		439996 TCPG_HUMAN (3-532): 0: 561: 28.33		LCK_HUMAN (3-449): 0: 517: 39.07
+	Hs
		902885 TCPH_HUMAN (4-532): 0: 591: 34.08		BLK_HUMAN (7-449): 1.77e-169: 487: 39.51
+	Hs
		902824 TCPB_HUMAN (1-535): 0: 586: 100.00		BLK_HUMAN (7-449): 1.77e-169: 487: 39.51
+	Hs
		486671 TCPG_HUMAN (3-532): 0: 561: 28.33		FGR_HUMAN (10-450): 3.39e-177: 508: 42.41
+	Hs
		881915 TCPG_HUMAN (3-532): 0: 561: 28.33		PTK6_HUMAN (1-451): 1.75e-176: 503: 100.00
+	Hs
		440441 TCPE_HUMAN (1-528): 0: 541: 32.29		FYN_HUMAN (10-450): 0: 520: 42.79
+	Hs
		439993 TCPE_HUMAN (1-528): 0: 541: 32.29		LCK_HUMAN (3-449): 0: 517: 39.07
+	Hs
		486670 TCPE_HUMAN (1-528): 0: 541: 32.29		FGR_HUMAN (10-450): 3.39e-177: 508: 42.41
+	Hs
		881834 TCPG_HUMAN (3-532): 0: 561: 28.33		BLK_HUMAN (7-449): 1.77e-169: 487: 39.51
+	Hs
		881890 TCPG_HUMAN (3-532): 0: 561: 28.33		ITK_HUMAN (7-447): 5.63e-153: 449: 32.60