HitPredict

Interactor 1: RED1 (P78563)
Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase)
Gene: ADARB1

Interactor 2: STAU2 (Q9NUL3)
Double-stranded RNA-binding protein Staufen homolog 2
Gene: STAU2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	A_deamin~dsrm, dsrm~dsrm
Common GO terms	GO:0003723 - RNA binding GO:0003725 - double-stranded RNA binding GO:0003729 - mRNA binding GO:0005730 - nucleolus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 741 Hs			1 570
+	Hs
		286943 RED1_HUMAN (1-741): 0: 850: 100.00		PRKRA_HUMAN (2-273): 4.63e-41: 152: 18.69
+	Hs
		345664 RED1_HUMAN (1-741): 0: 850: 100.00		STAU1_HUMAN (6-395): 1.39e-29: 125: 17.33
+	Hs
		624029 RED1_HUMAN (1-741): 0: 850: 100.00		E2AK2_HUMAN (10-212): 2.08e-26: 115: 21.46
+	Hs
		1008677 RED1_HUMAN (1-741): 0: 850: 100.00		RED1_HUMAN (306-423): 3.67e-19: 93.5: 27.50
+	Hs
		937211 RED1_HUMAN (1-741): 0: 850: 100.00		DSRAD_HUMAN (6-184): 4.4e-18: 90.4: 19.47
+	Hs
		1008904 RED1_HUMAN (1-741): 0: 850: 100.00		RED2_HUMAN (306-415): 1.52e-15: 82: 21.43
+	Hs
		1008743 RED1_HUMAN (1-741): 0: 850: 100.00		TRBP2_HUMAN (294-466): 8.53e-16: 81.2: 15.64
+	Hs
		1008705 RED1_HUMAN (1-741): 0: 850: 100.00		ILF3_HUMAN (274-428): 1.07e-11: 70: 21.38
+	Hs
		1008846 RED1_HUMAN (1-741): 0: 850: 100.00		STRBP_HUMAN (178-374): 1.88e-11: 68.9: 19.70
+	Hs
		286997 TRBP2_HUMAN (58-379): 1.31e-50: 182: 21.30		PRKRA_HUMAN (2-273): 4.63e-41: 152: 18.69
+	Dm
		1476080 SON_DROME (27-302): 1.47e-47: 183: 19.44		LOQS_DROME (7-379): 6.23e-34: 136: 16.20
+	Hs
		345872 TRBP2_HUMAN (58-379): 1.31e-50: 182: 21.30		STAU1_HUMAN (6-395): 1.39e-29: 125: 17.33
+	Hs
		624071 TRBP2_HUMAN (58-379): 1.31e-50: 182: 21.30		E2AK2_HUMAN (10-212): 2.08e-26: 115: 21.46
+	Dm
		1321069 Q8MRC7_DROME (2-300): 3.83e-57: 201: 24.14		ADAR_DROME (83-256): 2.53e-16: 84.2: 11.50
+	Hs
		937260 TRBP2_HUMAN (58-379): 1.31e-50: 182: 21.30		DSRAD_HUMAN (6-184): 4.4e-18: 90.4: 19.47
+	Rn
		92894 D3ZDD7_RAT (23-280): 4.65e-48: 182: 36.23		E2AK2_RAT (309-418): 9.71e-17: 85: 24.32
+	Hs
		1150646 TRBP2_HUMAN (58-379): 1.31e-50: 182: 21.30		TRBP2_HUMAN (294-466): 8.53e-16: 81.2: 15.64
+	Hs
		1089678 TRBP2_HUMAN (58-379): 1.31e-50: 182: 21.30		ILF3_HUMAN (274-428): 1.07e-11: 70: 21.38