HitPredict

Interactor 1: HTRA4 (P83105)
Serine protease HTRA4 (EC 3.4.21.-) (High-temperature requirement factor A4)
Gene: HTRA4

Interactor 2: S10AE (Q9HCY8)
Protein S100-A14 (S100 calcium-binding protein A14) (S114)
Gene: S100A14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	31470122
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 476 Hs			1 104
+	Hs
		682475 HTRA4_HUMAN (1-476): 0: 528: 100.00		S100P_HUMAN (15-103): 6.94e-30: 103: 22.58
+	Hs
		444953 HTRA4_HUMAN (1-476): 0: 528: 100.00		S10A9_HUMAN (14-101): 9.22e-29: 101: 29.03
+	Hs
		1013325 HTRA4_HUMAN (1-476): 0: 528: 100.00		S10AD_HUMAN (12-96): 3e-27: 97.2: 40.70
+	Hs
		1013321 HTRA4_HUMAN (1-476): 0: 528: 100.00		S10AG_HUMAN (12-102): 7.18e-27: 96.5: 20.83
+	Hs
		686800 HTRA4_HUMAN (1-476): 0: 528: 100.00		S10A4_HUMAN (17-97): 7.74e-27: 96.5: 27.06
+	Hs
		445162 HTRA4_HUMAN (1-476): 0: 528: 100.00		S10A6_HUMAN (17-97): 3.2e-23: 86.8: 25.30
+	Hs
		724557 HTRA4_HUMAN (1-476): 0: 528: 100.00		S10A7_HUMAN (16-101): 7.52e-20: 78.8: 19.78
+	Hs
		1013308 HTRA4_HUMAN (1-476): 0: 528: 100.00		S1A7A_HUMAN (16-101): 2.14e-19: 77.6: 19.78
+	Hs
		686790 CCN3_HUMAN (39-159): 4.07e-29: 119: 29.69		S10A4_HUMAN (17-97): 7.74e-27: 96.5: 27.06