Protein: CCN3
CCN family member 3 (Cellular communication network factor 3) (Insulin-like growth factor-binding protein 9) (IBP-9) (IGF-binding protein 9) (IGFBP-9) (Nephro blastoma-overexpressed gene protein homolog) (Protein NOV homolog) (NovH)

Gene: CCN3
Organism: Homo sapiens
Interactions: 37
UniProt ID: P48745

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0002062 - chondrocyte differentiation
GO:0005112 - Notch binding
GO:0005178 - integrin binding
GO:0005179 - hormone activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

626121

NFKB1
Nuclear factor NF-kappa-B p105 subunit

3

1

High-throughput

0.667

High

877596

TF65
Transcription factor p65

3

1

High-throughput

0.667

High

877605

Q8IV28
Nidogen-2

1

6

High-throughput

0.665

High

377822

IGF2
Insulin-like growth factor 2

1

2

Small-scale

0.647

High

420277

IGF1
Insulin-like growth factor 1

1

1

Small-scale

0.647

High

352009

RECK
Reversion-inducing cysteine-rich protein with Kazal motifs

1

1

High-throughput

0.621

High

877598

NID2
Nidogen-2

1

5

High-throughput

0.621

High

377455

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

Small-scale

0.614

High

877592

HXA1
Homeobox protein Hox-A1

3

2

High-throughput

0.609

High

694316

CO8A1
Collagen alpha-1(VIII) chain

2

1

High-throughput

0.606

High

877610

ZN330
Zinc finger protein 330

2

1

High-throughput

0.606

High

220227

FRS3
Fibroblast growth factor receptor substrate 3

2

0

High-throughput

0.580

High

877597

PO4F2
POU domain, class 4, transcription factor 2

2

0

High-throughput

0.580

High

877599

LCE1A
Late cornified envelope protein 1A

2

0

High-throughput

0.580

High

877600

KRA56
Keratin-associated protein 5-6

2

0

High-throughput

0.580

High

877607

TNIP3
TNFAIP3-interacting protein 3

2

0

High-throughput

0.580

High

877608

APOL6
Apolipoprotein L6

2

0

High-throughput

0.580

High

877609

LCE3D
Late cornified envelope protein 3D

2

0

High-throughput

0.580

High

857373

NOTC1
Neurogenic locus notch homolog protein 1

1

4

Small-scale

0.561

High

877593

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.541

High

877594

FXR2
RNA-binding protein FXR2

1

1

High-throughput

0.541

High

654476

FBLN1
Fibulin-1

1

9

Small-scale

0.527

High

720739

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.518

High

686790

S10A4
Protein S100-A4

1

0

Small-scale

0.504

High

389149

FINC
Fibronectin

1

2

Small-scale

0.501

High

447997

ITAV
Integrin alpha-V

1

1

Small-scale

0.501

High

877603

ANR11
Ankyrin repeat domain-containing protein 11

1

1

High-throughput

0.481

High

807983

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

Small-scale

0.480

High

877602

Q6P9E2
RECK protein

1

1

High-throughput

0.470

High

877611

X5D778
Ankyrin repeat domain 11 isoform A

1

1

High-throughput

0.470

High

877595

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

Small-scale

0.460

High

322587

FBX21
F-box only protein 21

1

0

High-throughput

0.458

High

667636

CDK2
Cyclin-dependent kinase 2

1

0

Small-scale

0.458

High

217954

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

877601

CK087
Uncharacterized protein C11orf87

2

0

High-throughput

0.316

High

877604

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

877606

MACOI
Macoilin

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025