HitPredict

Interactor 1: CPSF1 (Q10570)
Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit)
Gene: CPSF1

Interactor 2: CPSF3 (Q9UKF6)
Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73)
Gene: CPSF3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26496610, 31042468, 24981860, 33469008
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1443 Hs			1 684
+	Hs
		1014211 CPSF1_HUMAN (1-1443): 0: 1602: 100.00		CPSF2_HUMAN (12-640): 8.58e-180: 532: 19.17
+	At
		1320907 CPSF1_ARATH (2-1442): 0: 1072: 29.98		CPSF3_ARATH (6-683): 0: 686: 54.03
+	Sp
		142956 CFT1_SCHPO (1-1442): 0: 1040: 25.13		YSH1_SCHPO (5-682): 0: 649: 46.82
+	At
		1208877 CPSF1_ARATH (2-1442): 0: 1072: 29.98		CPS3B_ARATH (12-566): 2.29e-165: 490: 29.42
+	At
		1323026 CPSF1_ARATH (2-1442): 0: 1072: 29.98		CPSF2_ARATH (9-564): 4.62e-115: 364: 18.37
+	Sp
		251783 CFT1_SCHPO (1-1442): 0: 1040: 25.13		CFT2_SCHPO (27-373): 7.13e-81: 275: 23.50
+	Sc
		986638 CFT1_YEAST (3-678): 9.81e-115: 395: 18.62		YSH1_YEAST (4-683): 0: 589: 38.83
+	Sc
		988501 CFT1_YEAST (3-678): 9.81e-115: 395: 18.62		CFT2_YEAST (18-483): 4.75e-77: 265: 15.96