HitPredict

Interactor 1: ESC (Q24338)
Polycomb protein esc (Protein extra sex combs)
Gene: ESC

Interactor 2: CAF1 (Q24572)
Chromatin assembly factor 1 p55 subunit (CAF-1 p55 subunit) (CAF-1) (Nucleosome-remodeling factor 55 kDa subunit) (NURF-55)
Gene: Caf1-55

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 11124122, 12408863, 12408864, 24100017, 26063573, 29242288, 29070704, 12533794, 16537908
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CAF1C_H4-bd~WD40, WD40~WD40
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005700 - polytene chromosome
GO:0031491 - nucleosome binding
GO:0031507 - heterochromatin formation
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 425
Dm

1 430
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Last updated: 15 Jul 2024