Interactor 1: CWC2 (Q12046)
Pre-mRNA-splicing factor CWC2 (Complexed with CEF1 protein 2) (PRP19-associated complex protein 40) (Synthetic lethal with CLF1 protein 3)
Gene: CWC2

Interactor 2: CLF1 (Q12309)
Pre-mRNA-splicing factor CLF1 (Crooked neck-like factor 1) (PRP19-associated complex protein 77) (Synthetic lethal with CDC40 protein 3)
Gene: CLF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.733

The method score is based on:

Property Details
Experiments 12509417, 11884590, 16429126, 19016306, 37968396, 14690591
Identification Methods affinity chromatography technology, tandem affinity purification, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0071006 - U2-type catalytic step 1 spliceosome
GO:0071007 - U2-type catalytic step 2 spliceosome
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 339
Sc

1 687
+ Sc
+ Sp
+ Dm
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024