HitPredict

Interactor 1: PNRC1 (Q12796)
Proline-rich nuclear receptor coactivator 1 (Proline-rich protein 2) (Protein B4-2)
Gene: PNRC1

Interactor 2: DCP1A (Q9NPI6)
mRNA-decapping enzyme 1A (EC 3.6.1.62) (Smad4-interacting transcriptional co-activator) (Transcription factor SMIF)
Gene: DCP1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	30833792, 26496610, 24778252
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DCP1~PNRC
Common GO terms	GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000932 - P-body GO:0005634 - nucleus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 582
+	Hs
		1016556 PNRC1_HUMAN (1-327): 0: 528: 100.00		DCP1B_HUMAN (4-575): 2.69e-53: 193: 27.96
+	Hs
		1342875 PNRC2_HUMAN (208-326): 3.46e-52: 170: 41.32		DCP1A_HUMAN (1-582): 6.16e-85: 277: 100.00
+	Hs
		1224191 PNRC2_HUMAN (208-326): 3.46e-52: 170: 41.32		DCP1B_HUMAN (4-575): 2.69e-53: 193: 27.96