Interactor 1: ZP4 (Q12836)
Zona pellucida sperm-binding protein 4 (Zona pellucida glycoprotein 4) (Zp-4) (Zona pellucida protein B) [Cleaved into: Processed zona pellucida sperm-binding protein 4]
Gene: ZP4

Interactor 2: ZP4 (Q12836)
Zona pellucida sperm-binding protein 4 (Zona pellucida glycoprotein 4) (Zp-4) (Zona pellucida protein B) [Cleaved into: Processed zona pellucida sperm-binding protein 4]
Gene: ZP4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.49 1.00 0.701

The method score is based on:

Property Details
Experiments 26879157
Identification Methods electron microscopy, x-ray crystallography, infrared spectroscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Trefoil~Trefoil, Zona_pellucida~Zona_pellucida
Common GO terms GO:0002922 - positive regulation of humoral immune response
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0007339 - binding of sperm to zona pellucida
GO:0032190 - acrosin binding
and 8 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 540
Hs

1 540
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Gg
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024