HitPredict

Interactor 1: KIF5A (Q12840)
Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC)
Gene: KIF5A

Interactor 2: KLC3 (Q6P597)
Kinesin light chain 3 (KLC2-like) (kinesin light chain 2)
Gene: KLC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005871 - kinesin complex GO:0005874 - microtubule GO:0007018 - microtubule-based movement GO:0008017 - microtubule binding GO:0019894 - kinesin binding and 1 others more... GO:0035253 - ciliary rootlet
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1032 Hs			1 504
+	Hs
		1017559 KIF5A_HUMAN (1-1032): 1e-154: 487: 100.00		KLC2_HUMAN (15-499): 1.5e-87: 283: 56.17
+	Hs
		1160005 KI13B_HUMAN (7-730): 3.75e-110: 378: 23.68		KLC3_HUMAN (1-504): 1.73e-94: 297: 100.00
+	Ce
		712252 KINH_CAEEL (4-762): 1.74e-99: 334: 44.33		KLC_CAEEL (17-501): 9.29e-75: 247: 46.09
+	Hs
		992334 KIF5A_HUMAN (1-1032): 1e-154: 487: 100.00		KLC1_HUMAN (3-223): 4.34e-15: 79.7: 10.31
+	Mm
		702846 KIF5A_MOUSE (1-1032): 6.83e-152: 479: 97.29		Q8CD76_MOUSE (3-223): 1.09e-14: 78.5: 10.31
+	Hs
		231604 KIF1B_HUMAN (6-757): 2.78e-109: 376: 23.61		TMTC1_HUMAN (110-401): 1.4e-16: 84.9: 19.06
+	Ce
		712255 KINH_CAEEL (4-762): 1.74e-99: 334: 44.33		Q21592_CAEEL (264-485): 1.22e-13: 75.1: 17.78
+	Hs
		229869 KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20		KLC3_HUMAN (1-504): 1.73e-94: 297: 100.00
+	Hs
		702921 KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45		KLC3_HUMAN (1-504): 1.73e-94: 297: 100.00
+	Mm
		660001 KIF5C_MOUSE (477-1017): 2.72e-15: 83: 8.63		KLC3_MOUSE (1-503): 1.38e-91: 290: 89.94
+	Hs
		229887 KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20		KLC2_HUMAN (15-499): 1.5e-87: 283: 56.17
+	Hs
		702974 KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45		KLC2_HUMAN (15-499): 1.5e-87: 283: 56.17
+	Rn
		881490 KINH_RAT (623-1016): 2.52e-14: 79.9: 10.25		OGT1_RAT (4-448): 1.1e-54: 199: 18.05
+	Hs
		229891 KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20		KLC4_HUMAN (2-466): 5.1e-30: 125: 21.63
+	Hs
		702983 KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45		KLC4_HUMAN (2-466): 5.1e-30: 125: 21.63
+	Hs
		174664 KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45		OGT1_HUMAN (252-504): 1.4e-24: 110: 14.79
+	Hs
		101750 KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45		F8W6L3_HUMAN (284-503): 9.74e-22: 100: 31.53
+	Hs
		229856 KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20		KLC1_HUMAN (3-223): 4.34e-15: 79.7: 10.31
+	Hs
		702891 KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45		KLC1_HUMAN (3-223): 4.34e-15: 79.7: 10.31
+	Mm
		1143114 KINH_MOUSE (623-1016): 3.55e-14: 79.5: 10.00		Q8CD76_MOUSE (3-223): 1.09e-14: 78.5: 10.31