HitPredict

Interactor 1: SFSWA (Q12872)
Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog)
Gene: SFSWAP

Interactor 2: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	17353931, 33961781
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0048025 - negative regulation of mRNA splicing, via spliceosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 951 Hs			1 305
+	Hs
		1070498 SF3A1_HUMAN (160-789): 3.75e-47: 183: 11.15		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Hs
		1074265 SF3A1_HUMAN (160-789): 3.75e-47: 183: 11.15		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		198896 SF3A1_HUMAN (160-789): 3.75e-47: 183: 11.15		RFOX2_HUMAN (44-274): 2.32e-31: 122: 13.25
+	Hs
		1074282 SF3A1_HUMAN (160-789): 3.75e-47: 183: 11.15		RBM8A_HUMAN (95-239): 7.02e-31: 115: 21.38
+	Hs
		853905 SF3A1_HUMAN (160-789): 3.75e-47: 183: 11.15		NCBP2_HUMAN (128-271): 1.08e-30: 114: 18.06
+	Hs
		965152 ANK2_HUMAN (365-945): 4.52e-48: 189: 14.55		PABP3_HUMAN (153-248): 4.53e-17: 83.4: 26.04
+	Hs
		1246388 THOC2_HUMAN (500-927): 8.17e-14: 78.4: 12.01		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		516609 TITIN_HUMAN (124-936): 5.09e-11: 69.5: 9.00		PABP1_HUMAN (65-252): 1.33e-21: 96.9: 16.32
+	Hs
		1031405 TITIN_HUMAN (124-936): 5.09e-11: 69.5: 9.00		PABP4_HUMAN (153-248): 4.98e-19: 89.2: 27.08