Protein: WDR18
WD repeat-containing protein 18

Gene: WDR18
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q9BV38

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005656 - nuclear pre-replicative complex
GO:0005730 - nucleolus
GO:0006261 - DNA-templated DNA replication
GO:0006364 - rRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1316580

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

11

14

Small-scale

0.981

High

1414862

SENP3
Sentrin-specific protease 3

6

8

Small-scale

0.733

High

1414879

LAS1L
Ribosomal biogenesis protein LAS1L

6

3

Small-scale

0.726

High

1414870

TEX10
Testis-expressed protein 10

5

6

Small-scale

0.714

High

1211341

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

4

2

High-throughput

0.694

High

1111238

SNW1
SNW domain-containing protein 1

1

5

High-throughput

0.691

High

1414865

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

9

High-throughput

0.691

High

288753

NPM3
Nucleoplasmin-3

2

7

High-throughput

0.628

High

1313594

DDX60
Probable ATP-dependent RNA helicase DDX60

1

18

High-throughput

0.618

High

194325

R113A
E3 ubiquitin-protein ligase RNF113A

1

2

High-throughput

0.618

High

277805

H2AY
Core histone macro-H2A.1

1

12

High-throughput

0.618

High

591824

H2AX
Histone H2AX

1

10

High-throughput

0.618

High

854921

RECQ1
ATP-dependent DNA helicase Q1

1

18

High-throughput

0.618

High

980253

H4
Histone H4

1

9

High-throughput

0.618

High

1137497

SUZ12
Polycomb protein SUZ12

1

2

High-throughput

0.618

High

1155717

EZH2
Histone-lysine N-methyltransferase EZH2

1

19

High-throughput

0.618

High

1338933

NUP43
Nucleoporin Nup43

1

17

High-throughput

0.618

High

1414863

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

14

High-throughput

0.618

High

1414867

ANLN
Anillin

1

6

High-throughput

0.618

High

537821

HSP7C
Heat shock cognate 71 kDa protein

2

15

High-throughput

0.611

High

1367163

ESR2
Estrogen receptor beta

2

20

High-throughput

0.588

High

260396

BRD4
Bromodomain-containing protein 4

2

20

High-throughput

0.584

High

1234935

PKHA7
Pleckstrin homology domain-containing family A member 7

1

15

High-throughput

0.575

High

157803

CTRO
Citron Rho-interacting kinase

1

9

High-throughput

0.553

High

502112

H2AZ
Histone H2A.Z

1

11

High-throughput

0.553

High

971012

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

13

High-throughput

0.553

High

1227375

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.553

High

1255336

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.553

High

1400124

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

7

High-throughput

0.549

High

134137

IPO5
Importin-5

1

5

High-throughput

0.536

High

396850

ESR1
Estrogen receptor

1

20

High-throughput

0.536

High

447381

NPM
Nucleophosmin

1

7

High-throughput

0.536

High

625593

CSK22
Casein kinase II subunit alpha'

1

13

High-throughput

0.536

High

634606

LMNB1
Lamin-B1

1

12

High-throughput

0.536

High

854266

KI67
Proliferation marker protein Ki-67

1

11

High-throughput

0.536

High

859427

RL5
Large ribosomal subunit protein uL18

1

5

High-throughput

0.536

High

1014189

CBX1
Chromobox protein homolog 1

1

11

High-throughput

0.536

High

1114175

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1404359

CDC5L
Cell division cycle 5-like protein

1

10

High-throughput

0.536

High

1414866

EXOS4
Exosome complex component RRP41

1

10

High-throughput

0.536

High

1414872

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.536

High

1414873

PFD2
Prefoldin subunit 2

1

6

High-throughput

0.536

High

1414877

DRG1
Developmentally-regulated GTP-binding protein 1

1

7

High-throughput

0.536

High

242781

PRKN
E3 ubiquitin-protein ligase parkin

2

16

High-throughput

0.533

High

1391649

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

995235

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.508

High

1160569

SMN
Survival motor neuron protein

1

1

High-throughput

0.508

High

1414878

FBX7
F-box only protein 7

1

1

High-throughput

0.501

High

221963

FOXS1
Forkhead box protein S1

1

10

High-throughput

0.489

High

649408

H1T
Histone H1t

1

11

High-throughput

0.489

High

1406255

KIF2C
Kinesin-like protein KIF2C

1

8

High-throughput

0.489

High

1414859

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

4

High-throughput

0.489

High

1414861

FOXQ1
Forkhead box protein Q1

1

11

High-throughput

0.489

High

129386

MEN1
Menin

1

3

High-throughput

0.479

High

373029

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

589575

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

607064

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

696386

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

731579

STIP1
Stress-induced-phosphoprotein 1

1

13

High-throughput

0.479

High

769055

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

831349

CCNF
Cyclin-F

1

12

High-throughput

0.479

High

905096

MECP2
Methyl-CpG-binding protein 2

1

7

High-throughput

0.479

High

920250

PLK1
Serine/threonine-protein kinase PLK1

1

9

High-throughput

0.479

High

979188

RS6
Small ribosomal subunit protein eS6

1

4

High-throughput

0.479

High

1005045

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.479

High

1100320

TIF1B
Transcription intermediary factor 1-beta

1

12

High-throughput

0.479

High

1127127

RBM39
RNA-binding protein 39

1

11

High-throughput

0.479

High

1129725

MDC1
Mediator of DNA damage checkpoint protein 1

1

20

High-throughput

0.479

High

1161638

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.479

High

1235509

IFIX
Pyrin and HIN domain-containing protein 1

1

3

High-throughput

0.479

High

1257122

PAXI1
PAX-interacting protein 1

1

20

High-throughput

0.479

High

1280461

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

4

High-throughput

0.479

High

1314393

SLX4
Structure-specific endonuclease subunit SLX4

1

14

High-throughput

0.479

High

1328936

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

2

High-throughput

0.479

High

1330920

CGAS
Cyclic GMP-AMP synthase

1

2

High-throughput

0.479

High

1346912

SNIP1
Smad nuclear-interacting protein 1

1

3

High-throughput

0.479

High

1352723

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

1364235

TOPB1
DNA topoisomerase 2-binding protein 1

1

19

High-throughput

0.479

High

1368592

KAT6A
Histone acetyltransferase KAT6A

1

20

High-throughput

0.479

High

1391736

AURKB
Aurora kinase B

1

8

High-throughput

0.479

High

1393652

DDRGK
DDRGK domain-containing protein 1

1

4

High-throughput

0.479

High

1414858

FACD2
Fanconi anemia group D2 protein

1

2

High-throughput

0.479

High

1414864

ECT2
Protein ECT2

1

18

High-throughput

0.479

High

1414868

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

6

High-throughput

0.479

High

405538

KITH
Thymidine kinase, cytosolic

1

2

High-throughput

0.464

High

628015

ANXA7
Annexin A7

1

5

High-throughput

0.464

High

430307

JUN
Transcription factor Jun

1

13

High-throughput

0.445

High

1209602

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

High-throughput

0.445

High

1414871

GRHL1
Grainyhead-like protein 1 homolog

1

3

High-throughput

0.445

High

125599

LEG9
Galectin-9

1

7

High-throughput

0.437

High

272433

OBSL1
Obscurin-like protein 1

1

9

High-throughput

0.437

High

1135077

CUL7
Cullin-7

1

5

High-throughput

0.437

High

1178353

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

1286891

TM11B
Transmembrane protease serine 11B

1

1

High-throughput

0.437

High

1290693

ZCH18
Zinc finger CCCH domain-containing protein 18

1

18

High-throughput

0.437

High

1327167

FBXL6
F-box/LRR-repeat protein 6

1

2

High-throughput

0.437

High

1350435

BICD2
Protein bicaudal D homolog 2

1

13

High-throughput

0.437

High

1386949

GASP2
G-protein coupled receptor-associated sorting protein 2

1

1

High-throughput

0.437

High

1397388

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.437

High

1414860

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

1414869

DUS22
Dual specificity protein phosphatase 22

1

2

High-throughput

0.437

High

1414875

HECD1
E3 ubiquitin-protein ligase HECTD1

1

11

High-throughput

0.437

High

1414876

MOK
MAPK/MAK/MRK overlapping kinase

1

7

High-throughput

0.437

High

1414874

AGO1
Protein argonaute-1

1

0

High-throughput

0.426

High

1214186

LITD1
LINE-1 type transposase domain-containing protein 1

1

1

High-throughput

0.407

High

1414156

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

3

0

High-throughput

0.347

High

884218

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.279

Low

1120495

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.279

Low

1260413

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.279

Low

459332

CATL1
Procathepsin L

1

0

High-throughput

0.249

Low

888749

ACOT2
Acyl-coenzyme A thioesterase 2, mitochondrial

1

0

High-throughput

0.249

Low

1335177

NOA1
Nitric oxide-associated protein 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025