Interactor 1: PTPRJ (Q12913)
Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148)
Gene: PTPRJ

Interactor 2: PTPRJ (Q12913)
Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148)
Gene: PTPRJ

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.849

The method score is based on:

Property Details
Experiments 19167335, 15978577, 11526512
Identification Methods x-ray crystallography, comigration in sds page, tox-r dimerization assay, biochemical
Interaction Type association, direct interaction, dephosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~fn3, Y_phosphatase~Y_phosphatase
Common GO terms GO:0001525 - angiogenesis
GO:0001570 - vasculogenesis
GO:0001772 - immunological synapse
GO:0004725 - protein tyrosine phosphatase activity
GO:0005161 - platelet-derived growth factor receptor binding
and 46 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024