HitPredict

Interactor 1: MYO1E (Q12965)
Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E)
Gene: MYO1E

Interactor 2: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0016887 - ATP hydrolysis activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1108 Hs			1 1312
+	Hs
		724801 MYO1E_HUMAN (1-1108): 0: 1198: 100.00		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		1021686 MYO1E_HUMAN (1-1108): 0: 1198: 100.00		MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45
+	Hs
		148746 MYO1E_HUMAN (1-1108): 0: 1198: 100.00		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		724686 MYH9_HUMAN (3-1087): 0: 1020: 26.87		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		724943 MYH9_HUMAN (3-1087): 0: 1020: 26.87		MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45
+	Hs
		725065 MYO5B_HUMAN (8-1063): 0: 993: 26.25		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		724687 MYH9_HUMAN (3-1087): 0: 1020: 26.87		MYH10_HUMAN (44-596): 1.31e-16: 88.3: 13.20
+	Hs
		725097 MYH11_HUMAN (6-1087): 0: 1016: 26.34		MYH10_HUMAN (44-596): 1.31e-16: 88.3: 13.20
+	Hs
		522585 MYH7_HUMAN (7-973): 0: 989: 30.83		MYH7_HUMAN (524-1249): 1.05e-24: 114: 10.81
+	Mm
		93570 MYH9_MOUSE (3-1087): 0: 1024: 26.78		DESP_MOUSE (190-1069): 1.15e-11: 72: 18.72
+	Hs
		725095 MYH10_HUMAN (6-1087): 0: 1005: 26.78		MYH10_HUMAN (44-596): 1.31e-16: 88.3: 13.20
+	Rn
		361106 MYH6_RAT (12-872): 0: 979: 32.59		MYH6_RAT (524-1204): 1.16e-24: 114: 10.56
+	Hs
		1268114 MYO5B_HUMAN (8-1063): 0: 993: 26.25		MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45
+	Dm
		1303383 MYO7A_DROME (12-808): 0: 978: 35.17		MYSN_DROME (602-1200): 7.49e-24: 111: 9.15
+	Hs
		148460 MYH9_HUMAN (3-1087): 0: 1020: 26.87		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		148466 MYH11_HUMAN (6-1087): 0: 1016: 26.34		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		148461 MYH10_HUMAN (6-1087): 0: 1005: 26.78		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		522657 MYH7_HUMAN (7-973): 0: 989: 30.83		MYH4_HUMAN (785-1235): 1.33e-14: 81.7: 12.88