HitPredict

Interactor 1: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Interactor 2: SAV1 (Q9H4B6)
Protein salvador homolog 1 (45 kDa WW domain protein) (hWW45)
Gene: SAV1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.764

The method score is based on:

Property Details
Experiments 26186194, 24366813, 25692647, 28514442, 30266805, 33961781, 24255178, 27173435, 24981860, 36736316, 20562859, 23455922, 17517604, 16930133, 20920251, 23386615
Identification Methods affinity chromatography technology, proximity labelling technology, molecular sieving, nuclear magnetic resonance, anti tag coimmunoprecipitation, two hybrid, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0030216 - keratinocyte differentiation
GO:0035329 - hippo signaling
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024