HitPredict

Interactor 1: TRI32 (Q13049)
E3 ubiquitin-protein ligase TRIM32 (EC 2.3.2.27) (72 kDa Tat-interacting protein) (RING-type E3 ubiquitin transferase TRIM32) (Tripartite motif-containing protein 32) (Zinc finger protein HT2A)
Gene: TRIM32

Interactor 2: AKTIP (Q9H8T0)
AKT-interacting protein (Ft1) (Fused toes protein homolog)
Gene: AKTIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.905

Property	Details
Experiments	23414517, 26186194, 28514442, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 653 Hs			1 292
+	Hs
		1023307 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UB2E3_HUMAN (10-222): 2.23e-71: 220: 16.36
+	Hs
		919715 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UB2D2_HUMAN (74-222): 2.62e-71: 218: 19.33
+	Hs
		849316 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UB2D1_HUMAN (74-222): 8.21e-70: 214: 18.67
+	Hs
		895783 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UB2D3_HUMAN (74-222): 1.08e-69: 214: 19.33
+	Hs
		1023317 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UB2E2_HUMAN (10-222): 3.68e-68: 212: 14.95
+	Hs
		851808 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UB2E1_HUMAN (46-222): 3.32e-66: 206: 15.73
+	Hs
		896429 TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00		UBE2N_HUMAN (77-222): 8.9e-60: 189: 19.05
+	Hs
		1282350 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2E3_HUMAN (10-222): 2.23e-71: 220: 16.36
+	Hs
		1336390 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2D4_HUMAN (74-222): 2.02e-71: 218: 19.33
+	Hs
		919870 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2D2_HUMAN (74-222): 2.62e-71: 218: 19.33
+	Hs
		849453 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2D1_HUMAN (74-222): 8.21e-70: 214: 18.67
+	Hs
		895921 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2D3_HUMAN (74-222): 1.08e-69: 214: 19.33
+	Hs
		1297370 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2E2_HUMAN (10-222): 3.68e-68: 212: 14.95
+	Hs
		584923 RO52_HUMAN (6-470): 1.76e-111: 345: 14.62		UB2D2_HUMAN (74-222): 2.62e-71: 218: 19.33
+	Hs
		584907 RO52_HUMAN (6-470): 1.76e-111: 345: 14.62		UB2D1_HUMAN (74-222): 8.21e-70: 214: 18.67
+	Hs
		584916 RO52_HUMAN (6-470): 1.76e-111: 345: 14.62		UB2D3_HUMAN (74-222): 1.08e-69: 214: 19.33
+	Hs
		851889 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UB2E1_HUMAN (46-222): 3.32e-66: 206: 15.73
+	Hs
		584910 RO52_HUMAN (6-470): 1.76e-111: 345: 14.62		UB2E1_HUMAN (46-222): 3.32e-66: 206: 15.73
+	Hs
		896547 TRI39_HUMAN (11-469): 1.78e-113: 352: 13.43		UBE2N_HUMAN (77-222): 8.9e-60: 189: 19.05
+	Hs
		584918 RO52_HUMAN (6-470): 1.76e-111: 345: 14.62		UBE2N_HUMAN (77-222): 8.9e-60: 189: 19.05