HitPredict

Interactor 1: MKRN3 (Q13064)
Probable E3 ubiquitin-protein ligase makorin-3 (EC 2.3.2.27) (RING finger protein 63) (RING-type E3 ubiquitin transferase makorin-3) (Zinc finger protein 127)
Gene: MKRN3

Interactor 2: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	32460013, 33744966
Identification Methods	affinity chromatography technology, pull down, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:1990904 - ribonucleoprotein complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 507 Hs			1 644
+	Hs
		516487 MKRN3_HUMAN (1-507): 0: 599: 100.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		1031488 MKRN1_HUMAN (95-507): 0: 539: 53.61		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		1023561 MKRN3_HUMAN (1-507): 0: 599: 100.00		PABP3_HUMAN (1-644): 7.04e-175: 513: 68.98
+	Hs
		516728 MKRN1_HUMAN (95-507): 0: 539: 53.61		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		1031454 MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		516684 MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		1031384 ZC3H3_HUMAN (85-220): 2.61e-22: 103: 14.71		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		1288644 MKRN1_HUMAN (95-507): 0: 539: 53.61		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		1221460 ZC3H3_HUMAN (85-220): 2.61e-22: 103: 14.71		PABP3_HUMAN (1-644): 7.04e-175: 513: 68.98
+	Dm
		597087 Q9VP20_DROME (98-450): 1.42e-123: 368: 36.84		PABP_DROME (2-464): 6.23e-64: 224: 22.09
+	Hs
		1288624 MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33