Protein: PLAK
Junction plakoglobin (Desmoplakin III) (Desmoplakin-3)

Gene: PLAK, Jup
Organism: Mus musculus
Interactions: 32
UniProt ID: Q02257

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0001954 - positive regulation of cell-matrix adhesion
GO:0002159 - desmosome assembly
GO:0003713 - transcription coactivator activity
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

580363

CADH2
Cadherin-2

1

20

Small-scale

0.618

High

937529

CADH5
Cadherin-5

1

20

Small-scale

0.618

High

1036144

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

8

High-throughput

0.575

High

1036145

IASPP
RelA-associated inhibitor

1

10

Small-scale

0.575

High

1036142

PECA1
Platelet endothelial cell adhesion molecule

1

6

Small-scale

0.536

High

1036148

CE290
Centrosomal protein of 290 kDa

1

12

High-throughput

0.536

High

1036160

AHI1
Jouberin

1

20

High-throughput

0.536

High

1036146

MKS1
Tectonic-like complex member MKS1

1

1

High-throughput

0.489

High

1036156

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

High-throughput

0.489

High

684460

CTNA1
Catenin alpha-1

1

16

Small-scale

0.481

High

581959

INSR
Insulin receptor

1

20

Small-scale

0.479

High

655044

CXA1
Gap junction alpha-1 protein

1

9

Small-scale

0.479

High

686959

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

17

Small-scale

0.479

High

1036147

TFE3
Transcription factor E3

1

7

High-throughput

0.479

High

1036151

NEB2
Neurabin-2

1

20

High-throughput

0.479

High

1036152

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.479

High

1036154

WDTC1
WD and tetratricopeptide repeats protein 1

1

13

High-throughput

0.479

High

1036155

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

8

High-throughput

0.479

High

1036162

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

947669

NPHP4
Nephrocystin-4

1

0

High-throughput

0.458

High

1036158

FTM
Protein fantom

1

12

High-throughput

0.445

High

1036161

TRPM7
Transient receptor potential cation channel subfamily M member 7

1

2

Small-scale

0.445

High

504800

PTPRQ
Phosphatidylinositol phosphatase PTPRQ

1

20

Small-scale

0.437

High

554290

PCP2
Purkinje cell protein 2

1

1

Small-scale

0.437

High

1036143

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

14

High-throughput

0.437

High

1036150

TEDC2
Tubulin epsilon and delta complex protein 2

1

1

High-throughput

0.437

High

1036153

SPOP
Speckle-type POZ protein

1

12

High-throughput

0.437

High

1036157

CBAR1
CBY1-interacting BAR domain-containing protein 1

1

1

High-throughput

0.437

High

1036149

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

13

High-throughput

0.407

High

1036163

XPO7
Exportin-7

1

9

High-throughput

0.407

High

1036164

SRCN1
SRC kinase signaling inhibitor 1

1

5

High-throughput

0.407

High

1036159

TTC23
Tetratricopeptide repeat protein 23

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025