HitPredict

Interactor 1: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Interactor 2: Q9UQC1 (Q9UQC1)
Heat shock protein 72
Gene: HSP70-1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 416 Hs			1 151
+	Hs
		713954 TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00		HS71L_HUMAN (1-150): 2.61e-76: 240: 91.33
+	Hs
		503998 TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00		HSP7C_HUMAN (1-150): 6.81e-76: 239: 87.33
+	Hs
		1020988 TRAF2_HUMAN (3-415): 4e-124: 370: 38.01		Q9UQC1_HUMAN (1-151): 8.55e-83: 241: 100.00
+	Hs
		713952 TRAF2_HUMAN (3-415): 4e-124: 370: 38.01		HS71L_HUMAN (1-150): 2.61e-76: 240: 91.33
+	Hs
		503989 TRAF2_HUMAN (3-415): 4e-124: 370: 38.01		HSP7C_HUMAN (1-150): 6.81e-76: 239: 87.33
+	Mm
		565424 TRAF6_MOUSE (15-414): 1.94e-101: 313: 22.51		HSP72_MOUSE (1-150): 3.49e-83: 258: 84.87
+	Hs
		1357873 TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98		Q9UQC1_HUMAN (1-151): 8.55e-83: 241: 100.00
+	Hs
		714101 TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98		HS71L_HUMAN (1-150): 2.61e-76: 240: 91.33
+	Hs
		505009 TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98		HSP7C_HUMAN (1-150): 6.81e-76: 239: 87.33
+	Mm
		571853 TRAF6_MOUSE (15-414): 1.94e-101: 313: 22.51		HS71B_MOUSE (1-150): 8.69e-78: 244: 95.33
+	Mm
		926117 TRAF6_MOUSE (15-414): 1.94e-101: 313: 22.51		HSP7C_MOUSE (1-150): 6.81e-76: 239: 87.33