HitPredict

Interactor 1: ACACA (Q13085)
Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (Acetyl-Coenzyme A carboxylase alpha) (ACC-alpha)
Gene: ACACA

Interactor 2: ACACA (Q13085)
Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (Acetyl-Coenzyme A carboxylase alpha) (ACC-alpha)
Gene: ACACA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 29899443, 20457939
Identification Methods x-ray crystallography, molecular sieving, comigration in non denaturing gel electrophoresis, 3D electron microscopy
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ACC_central~ACC_central, ACC_central~Biotin_carb_N, ACC_central~Biotin_lipoyl, ACC_central~Carboxyl_trans, Biotin_carb_C~Biotin_carb_C, Biotin_carb_C~Biotin_carb_N, Biotin_carb_C~Biotin_lipoyl, Biotin_carb_C~Carboxyl_trans, Biotin_carb_C~CPSase_L_D2, Biotin_carb_N~Biotin_carb_N, Biotin_carb_N~Biotin_lipoyl, Biotin_carb_N~CPSase_L_D2, Biotin_lipoyl~Biotin_lipoyl, Biotin_lipoyl~Carboxyl_trans, Biotin_lipoyl~CPSase_L_D2, Carboxyl_trans~Carboxyl_trans, CPSase_L_D2~CPSase_L_D2
Common GO terms GO:0001650 - fibrillar center
GO:0001894 - tissue homeostasis
GO:0003989 - acetyl-CoA carboxylase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
and 11 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 2346
Hs

1 2346
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Last updated: 15 Jul 2024