Protein: TBCD1
TBC1 domain family member 1

Gene: TBCD1, TBC1D1
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q86TI0

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005634 - nucleus
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

730009

1433B
14-3-3 protein beta/alpha

6

20

High-throughput

0.735

High

966549

1433G
14-3-3 protein gamma

5

20

High-throughput

0.720

High

1287246

LNX1
E3 ubiquitin-protein ligase LNX

2

7

High-throughput

0.700

High

990425

1433Z
14-3-3 protein zeta/delta

4

20

High-throughput

0.699

High

971718

1433E
14-3-3 protein epsilon

4

3

Small-scale

0.697

High

247133

TBCD4
TBC1 domain family member 4

1

9

High-throughput

0.691

High

1287245

DP13B
DCC-interacting protein 13-beta

1

8

Small-scale

0.691

High

691188

1433T
14-3-3 protein theta

4

20

High-throughput

0.690

High

1049500

1433F
14-3-3 protein eta

5

20

High-throughput

0.654

High

976376

RB11A
Ras-related protein Rab-11A

1

15

High-throughput

0.618

High

725082

HXC8
Homeobox protein Hox-C8

2

4

High-throughput

0.606

High

1116671

RIN1
Ras and Rab interactor 1

2

1

High-throughput

0.606

High

1150117

TCEA2
Transcription elongation factor A protein 2

2

1

High-throughput

0.606

High

1185264

F161A
Protein FAM161A

2

1

High-throughput

0.606

High

1229354

LHX8
LIM/homeobox protein Lhx8

2

2

High-throughput

0.606

High

1287242

VPS52
Vacuolar protein sorting-associated protein 52 homolog

2

2

High-throughput

0.606

High

1287248

MCRS1
Microspherule protein 1

2

1

High-throughput

0.606

High

1287249

GMCL1
Germ cell-less protein-like 1

2

1

High-throughput

0.606

High

1287250

LMBL3
Lethal(3)malignant brain tumor-like protein 3

2

2

High-throughput

0.606

High

244724

ZC3H1
Zinc finger C3H1 domain-containing protein

2

0

High-throughput

0.602

High

1287241

FAM9B
Protein FAM9B

2

1

High-throughput

0.601

High

387125

TNNC2
Troponin C, skeletal muscle

3

8

High-throughput

0.591

High

1241427

ZFP1
Zinc finger protein 1 homolog

2

0

High-throughput

0.580

High

1287252

PNKP
Bifunctional polynucleotide phosphatase/kinase

2

0

High-throughput

0.580

High

1287260

FA50B
Protein FAM50B

2

0

High-throughput

0.580

High

1287255

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

Small-scale

0.561

High

341802

K2C75
Keratin, type II cytoskeletal 75

2

2

High-throughput

0.553

High

821138

TXLNA
Alpha-taxilin

2

3

High-throughput

0.553

High

1206395

EFHC2
EF-hand domain-containing family member C2

2

8

High-throughput

0.553

High

1287243

CC185
Coiled-coil domain-containing protein 185

2

5

High-throughput

0.553

High

1287247

SYTL4
Synaptotagmin-like protein 4

2

1

High-throughput

0.553

High

415682

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

1287256

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

20

Small-scale

0.512

High

1034171

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

20

Small-scale

0.489

High

1209004

PPR29
Protein phosphatase 1 regulatory subunit 29

1

5

High-throughput

0.489

High

1287254

SPXN
Spexin

1

1

High-throughput

0.489

High

1153825

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.486

High

1287253

BARD1
BRCA1-associated RING domain protein 1

1

2

High-throughput

0.479

High

1287259

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.458

High

1287262

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.458

High

1287251

UB2E2
Ubiquitin-conjugating enzyme E2 E2

1

1

High-throughput

0.457

High

516354

CALM1
Calmodulin-1

1

7

High-throughput

0.445

High

516428

CALM2
Calmodulin-2

1

7

High-throughput

0.445

High

516548

CALM3
Calmodulin-3

1

7

High-throughput

0.445

High

1258482

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

2

High-throughput

0.445

High

106193

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

1104208

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

2

High-throughput

0.437

High

1226979

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.437

High

1254444

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1287240

KSR1
Kinase suppressor of Ras 1

1

14

High-throughput

0.437

High

1287257

KI13B
Kinesin-like protein KIF13B

1

4

High-throughput

0.437

High

1287263

KCTD3
BTB/POZ domain-containing protein KCTD3

1

1

High-throughput

0.437

High

1287244

LIPB2
Liprin-beta-2

1

1

High-throughput

0.407

High

269262

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.316

High

1180454

C19L2
CWF19-like protein 2

2

0

High-throughput

0.316

High

1187645

T10IP
Testis-specific protein 10-interacting protein

2

0

High-throughput

0.316

High

1287261

LZTS1
Leucine zipper putative tumor suppressor 1

2

0

High-throughput

0.316

High

281362

GGYF1
GRB10-interacting GYF protein 1

1

0

High-throughput

0.249

Low

984182

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.249

Low

1287258

CING
Cingulin

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025