HitPredict

Interactor 1: UBP4 (Q13107)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein homolog)
Gene: USP4

Interactor 2: TRI25 (Q14258)
E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147)
Gene: TRIM25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37039823
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 963 Hs			1 630
+	Hs
		1052814 UBP15_HUMAN (1-924): 0: 749: 58.17		TRI25_HUMAN (1-630): 3.52e-149: 447: 100.00
+	Hs
		1024364 UBP4_HUMAN (1-963): 0: 908: 100.00		TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73
+	Hs
		1172416 UBP15_HUMAN (1-924): 0: 749: 58.17		TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73
+	Hs
		1190464 UBP15_HUMAN (1-924): 0: 749: 58.17		TRI46_HUMAN (4-622): 3.72e-69: 241: 15.24
+	Hs
		584941 UBP4_HUMAN (1-963): 0: 908: 100.00		RO52_HUMAN (72-325): 5.42e-14: 76.6: 13.36
+	Hs
		850096 UBP11_HUMAN (6-937): 0: 717: 44.60		TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73
+	Hs
		1318721 UBP15_HUMAN (1-924): 0: 749: 58.17		TRIM5_HUMAN (2-281): 6.42e-32: 131: 15.19
+	Hs
		537147 UBP15_HUMAN (1-924): 0: 749: 58.17		TRI27_HUMAN (2-358): 2.11e-31: 130: 14.40
+	Hs
		1290911 UBP15_HUMAN (1-924): 0: 749: 58.17		TRI11_HUMAN (6-288): 2.34e-31: 129: 19.08
+	Hs
		536761 UBP11_HUMAN (6-937): 0: 717: 44.60		TRI27_HUMAN (2-358): 2.11e-31: 130: 14.40
+	Hs
		585101 UBP15_HUMAN (1-924): 0: 749: 58.17		RO52_HUMAN (72-325): 5.42e-14: 76.6: 13.36
+	Hs
		301410 UBP19_HUMAN (183-937): 6.87e-148: 474: 30.87		TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73
+	Hs
		1198275 UBP37_HUMAN (164-938): 7.6e-90: 309: 14.43		TRIM4_HUMAN (169-628): 1.89e-78: 259: 14.87
+	Hs
		1172456 UBP16_HUMAN (245-922): 2.34e-97: 326: 17.57		TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73
+	Hs
		301359 UBP19_HUMAN (183-937): 6.87e-148: 474: 30.87		RO52_HUMAN (72-325): 5.42e-14: 76.6: 13.36
+	Hs
		271187 UBP2_HUMAN (604-928): 8.22e-65: 231: 23.55		TRIM8_HUMAN (7-358): 1.75e-77: 258: 25.21
+	Hs
		777049 UBP8_HUMAN (546-932): 1.79e-62: 232: 22.06		TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73
+	Hs
		271128 UBP2_HUMAN (604-928): 8.22e-65: 231: 23.55		TRI46_HUMAN (4-622): 3.72e-69: 241: 15.24
+	Hs
		271027 UBP2_HUMAN (604-928): 8.22e-65: 231: 23.55		TRI27_HUMAN (2-358): 2.11e-31: 130: 14.40
+	Hs
		271032 UBP2_HUMAN (604-928): 8.22e-65: 231: 23.55		RO52_HUMAN (72-325): 5.42e-14: 76.6: 13.36