HitPredict

Interactor 1: CAF1B (Q13112)
Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (M-phase phosphoprotein 7)
Gene: CHAF1B

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	27705803, 20850016, 24981860, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 559 Hs			1 183
+	Hs
		800362 CAF1B_HUMAN (1-559): 1.02e-137: 412: 100.00		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		949767 CAF1B_HUMAN (1-559): 1.02e-137: 412: 100.00		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Mm
		1143045 CAF1B_MOUSE (1-559): 1.03e-128: 389: 82.69		CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89
+	Hs
		316029 CAF1B_HUMAN (1-559): 1.02e-137: 412: 100.00		CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78
+	Hs
		903191 WDR5_HUMAN (2-94): 9.73e-14: 74.3: 24.21		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		800458 DAW1_HUMAN (308-459): 6.78e-22: 100: 9.80		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		903125 WDR5_HUMAN (2-94): 9.73e-14: 74.3: 24.21		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		203735 DAW1_HUMAN (308-459): 6.78e-22: 100: 9.80		SUV91_HUMAN (3-179): 4.73e-40: 141: 16.20
+	Hs
		1335779 NLE1_HUMAN (329-440): 1.36e-17: 87.8: 10.71		CBX8_HUMAN (21-116): 2.34e-26: 104: 32.00
+	Hs
		903532 WDR5_HUMAN (2-94): 9.73e-14: 74.3: 24.21		CBX8_HUMAN (21-116): 2.34e-26: 104: 32.00