HitPredict

Interactor 1: TRAF3 (Q13114)
TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3)
Gene: TRAF3

Interactor 2: TNR18 (Q9Y5U5)
Tumor necrosis factor receptor superfamily member 18 (Activation-inducible TNFR family receptor) (Glucocorticoid-induced TNFR-related protein) (CD antigen CD357)
Gene: TNFRSF18

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	10037686, 15944293
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006915 - apoptotic process GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 568 Hs			1 241
+	Hs
		639578 TRAF3_HUMAN (1-568): 1.45e-163: 479: 100.00		TNR5_HUMAN (34-224): 3.5e-48: 161: 17.86
+	Mm
		192587 TRAF3_MOUSE (1-568): 3.65e-163: 478: 96.13		TNR11_MOUSE (28-190): 1.46e-44: 159: 21.56
+	Hs
		1024798 TRAF3_HUMAN (1-568): 1.45e-163: 479: 100.00		TNR11_HUMAN (28-190): 9.86e-44: 157: 25.15
+	Hs
		989744 TRAF3_HUMAN (1-568): 1.45e-163: 479: 100.00		TNR9_HUMAN (34-226): 2.75e-42: 146: 25.23
+	Hs
		738661 TRAF3_HUMAN (1-568): 1.45e-163: 479: 100.00		TNR3_HUMAN (34-214): 3.38e-39: 142: 18.95
+	Mm
		648958 TRAF3_MOUSE (1-568): 3.65e-163: 478: 96.13		TNR5_MOUSE (26-224): 9.98e-38: 135: 17.96
+	Mm
		591448 TRAF3_MOUSE (1-568): 3.65e-163: 478: 96.13		TNR9_MOUSE (34-222): 4.69e-37: 132: 24.88
+	Hs
		591320 TRAF3_HUMAN (1-568): 1.45e-163: 479: 100.00		TNR1B_HUMAN (34-169): 2.17e-34: 129: 22.38
+	Mm
		838553 TRAF3_MOUSE (1-568): 3.65e-163: 478: 96.13		TNR3_MOUSE (15-213): 2.59e-31: 120: 18.10
+	Hs
		796825 TRAF3_HUMAN (1-568): 1.45e-163: 479: 100.00		TNR4_HUMAN (35-167): 7.72e-28: 108: 23.72
+	Mm
		812913 TRAF3_MOUSE (1-568): 3.65e-163: 478: 96.13		TNR4_MOUSE (34-167): 7.45e-26: 103: 24.53
+	Hs
		1024725 TRAF3_HUMAN (1-568): 1.45e-163: 479: 100.00		TNR14_HUMAN (28-135): 4.69e-23: 96.4: 25.86
+	Mm
		192584 TRAF5_MOUSE (10-567): 4.83e-133: 401: 41.36		TNR11_MOUSE (28-190): 1.46e-44: 159: 21.56
+	Hs
		129532 TRAF5_HUMAN (12-567): 9.32e-132: 397: 40.79		TNR5_HUMAN (34-224): 3.5e-48: 161: 17.86
+	Mm
		936208 TRAF5_MOUSE (10-567): 4.83e-133: 401: 41.36		TNR14_MOUSE (28-233): 2.48e-43: 149: 25.12
+	Hs
		129536 TRAF5_HUMAN (12-567): 9.32e-132: 397: 40.79		TNR3_HUMAN (34-214): 3.38e-39: 142: 18.95
+	Hs
		436620 TRAF3_HUMAN (1-568): 1.45e-163: 479: 100.00		TNR16_HUMAN (28-157): 9.7e-10: 59.8: 15.04
+	Mm
		838552 TRAF5_MOUSE (10-567): 4.83e-133: 401: 41.36		TNR3_MOUSE (15-213): 2.59e-31: 120: 18.10
+	Hs
		129538 TRAF5_HUMAN (12-567): 9.32e-132: 397: 40.79		TNR4_HUMAN (35-167): 7.72e-28: 108: 23.72
+	Hs
		129526 TRAF5_HUMAN (12-567): 9.32e-132: 397: 40.79		TNR16_HUMAN (28-157): 9.7e-10: 59.8: 15.04