Interactor 1: REST (Q13127)
RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor)
Gene: REST
Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27634302 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus and 3 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
