HitPredict

Interactor 1: CDK16 (Q00536)
Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)
Gene: CDK16

Interactor 2: CCYL1 (Q8N7R7)
Cyclin-Y-like protein 1
Gene: CCNYL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.968

Property	Details
Experiments	25852190, 26186194, 26496610, 28514442, 33961781, 32707033, 22184064
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cyclin_N~Pkinase
Common GO terms	GO:0005886 - plasma membrane GO:0007283 - spermatogenesis
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 496 Hs			1 359
+	Mm
		92609 CDK16_MOUSE (1-496): 5.99e-176: 505: 97.58		CCYL1_MOUSE (10-359): 0: 574: 92.39
+	Hs
		1025626 CDK17_HUMAN (4-492): 2.86e-154: 451: 67.95		CCYL1_HUMAN (1-359): 0: 612: 100.00
+	Hs
		1025570 CDK16_HUMAN (1-496): 5.5e-177: 507: 100.00		CCNY_HUMAN (1-359): 0: 550: 70.25
+	Mm
		1048189 CDK16_MOUSE (1-496): 5.99e-176: 505: 97.58		CCNY_MOUSE (1-359): 0: 547: 69.97
+	Hs
		322110 CDK14_HUMAN (159-474): 5.72e-130: 387: 60.19		CCNY_HUMAN (1-359): 0: 550: 70.25
+	Mm
		204895 CDK14_MOUSE (159-474): 3.22e-130: 387: 60.19		CCNY_MOUSE (1-359): 0: 547: 69.97
+	Ce
		759752 CDK17_CAEEL (17-473): 1.57e-135: 408: 54.80		CCNY_CAEEL (1-359): 0: 508: 49.60
+	Dm
		120686 M9PE01_DROME (4-479): 3.83e-133: 397: 43.81		Q9VKF0_DROME (1-359): 0: 515: 51.34
+	Dm
		1267439 Q7KM03_DROME (4-479): 5.65e-133: 396: 43.81		Q9VKF0_DROME (1-359): 0: 515: 51.34