Protein: CDK14
Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)

Gene: CDK14
Organism: Homo sapiens
Interactions: 48
UniProt ID: O94921

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0000308 - cytoplasmic cyclin-dependent protein kinase holoenzyme complex
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

322094

CDN1A
Cyclin-dependent kinase inhibitor 1

5

20

Small-scale

0.940

High

322110

CCNY
Cyclin-Y

3

9

Small-scale

0.880

High

322099

CDK5
Cyclin-dependent kinase 5

3

18

High-throughput

0.861

High

322100

CDK17
Cyclin-dependent kinase 17

3

18

High-throughput

0.861

High

322120

CILK1
Serine/threonine-protein kinase ICK

3

18

High-throughput

0.861

High

322077

CDK14
Cyclin-dependent kinase 14

3

19

Small-scale

0.827

High

322086

FGR
Tyrosine-protein kinase Fgr

2

14

High-throughput

0.811

High

322092

CCND3
G1/S-specific cyclin-D3

1

20

Small-scale

0.766

High

322081

RASK
GTPase KRas

2

14

High-throughput

0.754

High

322107

HS905
Putative heat shock protein HSP 90-alpha A5

2

20

High-throughput

0.712

High

322101

1433F
14-3-3 protein eta

4

20

Small-scale

0.703

High

322095

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

20

High-throughput

0.691

High

322103

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

6

High-throughput

0.691

High

322113

CDKL2
Cyclin-dependent kinase-like 2

1

18

High-throughput

0.691

High

322114

RBM14
RNA-binding protein 14

1

12

High-throughput

0.691

High

322115

CDK15
Cyclin-dependent kinase 15

1

18

High-throughput

0.691

High

322093

1433B
14-3-3 protein beta/alpha

3

20

Small-scale

0.677

High

322091

1433T
14-3-3 protein theta

3

20

Small-scale

0.674

High

322117

ELL3
RNA polymerase II elongation factor ELL3

3

1

High-throughput

0.667

High

322085

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.665

High

322096

1433G
14-3-3 protein gamma

3

20

High-throughput

0.662

High

322097

1433E
14-3-3 protein epsilon

2

9

Small-scale

0.644

High

251488

CCNT1
Cyclin-T1

1

20

High-throughput

0.618

High

322080

RASH
GTPase HRas

1

13

High-throughput

0.618

High

322084

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

322104

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.618

High

322106

LARP7
La-related protein 7

1

19

High-throughput

0.618

High

322118

ANLN
Anillin

1

3

High-throughput

0.618

High

322083

RB
Retinoblastoma-associated protein

2

10

Small-scale

0.602

High

322119

GDE1
Glycerophosphodiester phosphodiesterase 1

2

0

High-throughput

0.602

High

322102

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

4

High-throughput

0.575

High

322087

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.536

High

322098

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

322112

SEPT8
Septin-8

1

5

Small-scale

0.504

High

322121

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

322078

HEXI1
Protein HEXIM1

1

8

High-throughput

0.479

High

322079

KI20A
Kinesin-like protein KIF20A

1

8

High-throughput

0.479

High

322082

IGHA2
Immunoglobulin heavy constant alpha 2

1

6

High-throughput

0.479

High

322088

EF2
Elongation factor 2

1

8

High-throughput

0.479

High

322089

MIF
Macrophage migration inhibitory factor

1

3

High-throughput

0.479

High

322105

H2B2E
Histone H2B type 2-E

1

7

High-throughput

0.479

High

322109

SERB1
SERPINE1 mRNA-binding protein 1

1

10

High-throughput

0.479

High

322116

EGLN3
Prolyl hydroxylase EGLN3

1

5

High-throughput

0.479

High

47480

RPSA2
Small ribosomal subunit protein uS2B

1

3

High-throughput

0.445

High

322090

DDX5
Probable ATP-dependent RNA helicase DDX5

1

5

High-throughput

0.445

High

322108

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

3

High-throughput

0.445

High

322111

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025