Interactor 1: PAK1 (Q13153)
Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)
Gene: PAK1

Interactor 2: MYLK (Q15746)
Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]
Gene: MYLK

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.735

The method score is based on:

Property Details
Experiments 10092231
Identification Methods enzymatic study, protein kinase assay
Interaction Type direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains PBD~Pkinase, Pkinase~fn3, I-set~Pkinase, Pkinase~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006468 - protein phosphorylation
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 545
Hs

1 1914
+ Hs
+ Hs
+ Mm
+ Hs

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Last updated: 15 Jul 2024