HitPredict

Interactor 1: PRDX4 (Q13162)
Peroxiredoxin-4 (EC 1.11.1.24) (Antioxidant enzyme AOE372) (AOE37-2) (Peroxiredoxin IV) (Prx-IV) (Thioredoxin peroxidase AO372) (Thioredoxin-dependent peroxide reductase A0372) (Thioredoxin-dependent peroxiredoxin 4)
Gene: PRDX4

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21182203
Identification Methods	affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 271 Hs			1 530
+	Hs
		670988 PRDX3_HUMAN (29-271): 1.53e-112: 326: 54.44		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369520 PRDX4_HUMAN (1-271): 3.79e-128: 366: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		685741 PRDX2_HUMAN (74-271): 2.45e-105: 305: 68.69		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369052 PRDX3_HUMAN (29-271): 1.53e-112: 326: 54.44		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369073 PRDX2_HUMAN (74-271): 2.45e-105: 305: 68.69		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		611429 PRDX4_HUMAN (1-271): 3.79e-128: 366: 100.00		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Hs
		377120 PRDX3_HUMAN (29-271): 1.53e-112: 326: 54.44		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Rn
		415149 PRDX1_RAT (74-269): 3.96e-102: 297: 68.53		GCR_RAT (3-495): 5.89e-100: 321: 23.03
+	Hs
		487392 PRDX4_HUMAN (1-271): 3.79e-128: 366: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		414494 PRDX1_HUMAN (74-269): 7.22e-102: 297: 68.53		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		487366 PRDX1_HUMAN (74-269): 7.22e-102: 297: 68.53		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59