Protein: RELB
Transcription factor RelB (I-Rel)

Gene: RELB
Organism: Homo sapiens
Interactions: 137
UniProt ID: Q01201

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

626184

NFKB1
Nuclear factor NF-kappa-B p105 subunit

14

18

Small-scale

0.981

High

1029985

TF65
Transcription factor p65

14

18

Small-scale

0.981

High

1026698

NFKB2
Nuclear factor NF-kappa-B p100 subunit

14

17

Small-scale

0.981

High

683441

IKBA
NF-kappa-B inhibitor alpha

8

20

Small-scale

0.964

High

1029986

REL
Proto-oncogene c-Rel

5

19

Small-scale

0.922

High

127779

IKBE
NF-kappa-B inhibitor epsilon

4

20

High-throughput

0.895

High

1029998

IKBB
NF-kappa-B inhibitor beta

1

20

High-throughput

0.691

High

1030021

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

3

7

High-throughput

0.667

High

1030028

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

3

6

High-throughput

0.667

High

1030029

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

5

Small-scale

0.647

High

903132

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

2

13

High-throughput

0.628

High

1030004

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

2

6

High-throughput

0.628

High

1030013

TNIP2
TNFAIP3-interacting protein 2

2

5

High-throughput

0.628

High

1030049

KLH20
Kelch-like protein 20

2

1

High-throughput

0.628

High

1030000

EZH2
Histone-lysine N-methyltransferase EZH2

2

8

Small-scale

0.624

High

1030015

SMRC2
SWI/SNF complex subunit SMARCC2

2

20

High-throughput

0.621

High

1030020

SMRC1
SWI/SNF complex subunit SMARCC1

2

11

High-throughput

0.621

High

606643

CEBPB
CCAAT/enhancer-binding protein beta

1

11

High-throughput

0.618

High

1029983

RELB
Transcription factor RelB

1

18

High-throughput

0.618

High

1030019

REQU
Zinc finger protein ubi-d4

2

20

Small-scale

0.611

High

1030045

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

2

2

Small-scale

0.602

High

253611

IMA7
Importin subunit alpha-7

2

9

High-throughput

0.601

High

777266

AHR
Aryl hydrocarbon receptor

2

11

Small-scale

0.601

High

907383

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

2

6

High-throughput

0.601

High

910855

IMA1
Importin subunit alpha-1

2

9

High-throughput

0.601

High

1030025

FBXW7
F-box/WD repeat-containing protein 7

2

12

High-throughput

0.601

High

1030046

DAXX
Death domain-associated protein 6

2

1

Small-scale

0.601

High

891462

GSK3B
Glycogen synthase kinase-3 beta

1

9

Small-scale

0.597

High

142208

CCL22
C-C motif chemokine 22

2

20

Small-scale

0.584

High

712743

IL12B
Interleukin-12 subunit beta

2

6

Small-scale

0.584

High

911215

IMA5
Importin subunit alpha-5

2

9

High-throughput

0.584

High

1030023

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

9

Small-scale

0.584

High

1030032

CCL19
C-C motif chemokine 19

2

20

Small-scale

0.584

High

1030038

NEK6
Serine/threonine-protein kinase Nek6

1

11

Small-scale

0.573

High

443314

CDK1
Cyclin-dependent kinase 1

1

4

High-throughput

0.541

High

459270

CATL1
Procathepsin L

1

3

High-throughput

0.541

High

1030006

COMD2
COMM domain-containing protein 2

1

3

Small-scale

0.536

High

1030011

COMD1
COMM domain-containing protein 1

1

4

Small-scale

0.536

High

1030026

EFMT3
EEF1A lysine methyltransferase 3

1

4

High-throughput

0.536

High

1030031

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

15

High-throughput

0.536

High

1030033

COMD5
COMM domain-containing protein 5

1

2

Small-scale

0.536

High

1030034

COMD4
COMM domain-containing protein 4

1

2

Small-scale

0.536

High

1030041

COMD8
COMM domain-containing protein 8

1

2

Small-scale

0.536

High

1030042

COMD9
COMM domain-containing protein 9

1

1

Small-scale

0.536

High

1030050

COMDA
COMM domain-containing protein 10

1

17

Small-scale

0.536

High

833529

BUD31
Protein BUD31 homolog

1

0

High-throughput

0.518

High

1029989

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

0

High-throughput

0.518

High

1030010

MT1M
Metallothionein-1M

1

0

High-throughput

0.518

High

355196

ACL6A
Actin-like protein 6A

1

9

High-throughput

0.515

High

903322

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

13

High-throughput

0.515

High

1029988

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

2

High-throughput

0.515

High

1029992

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

Small-scale

0.515

High

1030003

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

2

High-throughput

0.515

High

1030024

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

11

High-throughput

0.515

High

1030044

HDAC6
Protein deacetylase HDAC6

1

20

High-throughput

0.515

High

1030036

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

4

High-throughput

0.501

High

988288

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

Small-scale

0.493

High

172711

XPO1
Exportin-1

1

11

High-throughput

0.479

High

177847

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

20

High-throughput

0.479

High

252963

PDE8A
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A

1

4

Small-scale

0.479

High

378061

TNFA
Tumor necrosis factor

1

15

Small-scale

0.479

High

378371

IFNB
Interferon beta

1

7

Small-scale

0.479

High

378559

IL1B
Interleukin-1 beta

1

7

Small-scale

0.479

High

408025

TBB4A
Tubulin beta-4A chain

1

18

High-throughput

0.479

High

428369

RLA2
Large ribosomal subunit protein P2

1

2

High-throughput

0.479

High

457371

TBB5
Tubulin beta chain

1

18

High-throughput

0.479

High

460502

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

3

High-throughput

0.479

High

507165

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

5

High-throughput

0.479

High

518779

IL8
Interleukin-8

1

15

Small-scale

0.479

High

534944

BIP
Endoplasmic reticulum chaperone BiP

1

20

High-throughput

0.479

High

536988

HSP7C
Heat shock cognate 71 kDa protein

1

20

High-throughput

0.479

High

543492

VDR
Vitamin D3 receptor

1

20

Small-scale

0.479

High

562890

CCL5
C-C motif chemokine 5

1

20

Small-scale

0.479

High

587624

DESP
Desmoplakin

1

8

High-throughput

0.479

High

600793

HSP76
Heat shock 70 kDa protein 6

1

20

High-throughput

0.479

High

608863

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

2

High-throughput

0.479

High

643456

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.479

High

651282

CBL
E3 ubiquitin-protein ligase CBL

1

12

Small-scale

0.479

High

655157

SFPQ
Splicing factor, proline- and glutamine-rich

1

6

High-throughput

0.479

High

675464

TYY1
Transcriptional repressor protein YY1

1

10

Small-scale

0.479

High

681622

PSA4
Proteasome subunit alpha type-4

1

4

High-throughput

0.479

High

684977

DNMT1
DNA

1

4

Small-scale

0.479

High

697499

PYR1
Multifunctional protein CAD

1

4

High-throughput

0.479

High

700611

PSA5
Proteasome subunit alpha type-5

1

3

Small-scale

0.479

High

761372

HS71L
Heat shock 70 kDa protein 1-like

1

20

High-throughput

0.479

High

801271

HSPA9
Stress-70 protein, mitochondrial

1

20

High-throughput

0.479

High

860491

RS5
Small ribosomal subunit protein uS7

1

1

High-throughput

0.479

High

860713

RS10
Small ribosomal subunit protein eS10

1

3

High-throughput

0.479

High

906392

DHB4
Peroxisomal multifunctional enzyme type 2

1

1

High-throughput

0.479

High

927238

ATX1
Ataxin-1

1

4

High-throughput

0.479

High

972367

RS14
Small ribosomal subunit protein uS11

1

3

High-throughput

0.479

High

973402

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.479

High

984381

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.479

High

993136

ACTG
Actin, cytoplasmic 2

1

8

High-throughput

0.479

High

1008091

PRKDC
DNA-dependent protein kinase catalytic subunit

1

9

High-throughput

0.479

High

1014476

SMAD3
Mothers against decapentaplegic homolog 3

1

7

Small-scale

0.479

High

1025325

CDK6
Cyclin-dependent kinase 6

1

8

Small-scale

0.479

High

1025980

CLH1
Clathrin heavy chain 1

1

4

High-throughput

0.479

High

1027385

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

8

High-throughput

0.479

High

1029987

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.479

High

1029990

SKP2
S-phase kinase-associated protein 2

1

5

Small-scale

0.479

High

1029991

SMAD4
Mothers against decapentaplegic homolog 4

1

7

Small-scale

0.479

High

1029993

IMB1
Importin subunit beta-1

1

5

High-throughput

0.479

High

1029994

SUZ12
Polycomb protein SUZ12

1

2

Small-scale

0.479

High

1029996

NONO
Non-POU domain-containing octamer-binding protein

1

7

High-throughput

0.479

High

1029997

IRF4
Interferon regulatory factor 4

1

20

Small-scale

0.479

High

1029999

SMAD2
Mothers against decapentaplegic homolog 2

1

7

Small-scale

0.479

High

1030001

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

13

High-throughput

0.479

High

1030002

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

3

High-throughput

0.479

High

1030005

TAXB1
Tax1-binding protein 1

1

4

High-throughput

0.479

High

1030007

IFNL1
Interferon lambda-1

1

7

Small-scale

0.479

High

1030008

IFNL3
Interferon lambda-3

1

7

Small-scale

0.479

High

1030009

CCAR2
Cell cycle and apoptosis regulator protein 2

1

2

High-throughput

0.479

High

1030012

ARI1B
AT-rich interactive domain-containing protein 1B

1

11

High-throughput

0.479

High

1030017

DDX1
ATP-dependent RNA helicase DDX1

1

6

High-throughput

0.479

High

1030018

CCL17
C-C motif chemokine 17

1

20

Small-scale

0.479

High

1030022

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

8

High-throughput

0.479

High

1030027

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

7

Small-scale

0.479

High

1030039

SIX2
Homeobox protein SIX2

1

6

Small-scale

0.479

High

1030048

RUVB1
RuvB-like 1

1

7

High-throughput

0.479

High

1030051

ZHX2
Zinc fingers and homeoboxes protein 2

1

3

Small-scale

0.479

High

228233

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

591419

NQO2
Ribosyldihydronicotinamide dehydrogenase [quinone]

1

0

High-throughput

0.458

High

1029995

TCAL1
Transcription elongation factor A protein-like 1

1

0

High-throughput

0.458

High

1030035

APC1
Anaphase-promoting complex subunit 1

1

0

Small-scale

0.458

High

1030040

XPP3
Xaa-Pro aminopeptidase 3

1

0

High-throughput

0.458

High

552943

PIP
Prolactin-inducible protein

1

4

High-throughput

0.445

High

1030043

COMD3
COMM domain-containing protein 3

1

1

Small-scale

0.445

High

416009

CP1A1
Cytochrome P450 1A1

1

1

Small-scale

0.437

High

1030014

RLA0L
Putative ribosomal protein uL10-like

1

2

High-throughput

0.437

High

1030030

Q96TA9
SWI related protein

1

15

High-throughput

0.437

High

1030037

Q9H836
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

2

High-throughput

0.437

High

1030047

Q9UQC1
Heat shock protein 72

1

20

High-throughput

0.437

High

1029984

DIAC
Di-N-acetylchitobiase

2

0

High-throughput

0.328

High

869147

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.282

High

1030016

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025