HitPredict

Interactor 1: PAK2 (Q13177)
Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (Gamma-PAK) (PAK65) (S6/H4 kinase) (p21-activated kinase 2) (PAK-2) (p58) [Cleaved into: PAK-2p27 (p27); PAK-2p34 (p34) (C-t-PAK2)]
Gene: PAK2

Interactor 2: SCLT1 (Q96NL6)
Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1)
Gene: SCLT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26638075
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 524 Hs			1 688
+	Hs
		725152 PAK2_HUMAN (1-524): 0: 538: 100.00		MYH10_HUMAN (350-686): 3.14e-11: 69.2: 11.70
+	Hs
		528359 KAPCB_HUMAN (207-524): 1.39e-130: 385: 22.94		MYH6_HUMAN (2-685): 5.79e-29: 126: 11.65
+	Hs
		528371 STK3_HUMAN (224-524): 1.89e-125: 377: 41.25		MYH6_HUMAN (2-685): 5.79e-29: 126: 11.65
+	Hs
		551616 AKT1_HUMAN (141-523): 1.99e-133: 397: 21.83		DESP_HUMAN (1-661): 7.45e-20: 97.1: 14.39
+	Hs
		1027458 STK3_HUMAN (224-524): 1.89e-125: 377: 41.25		MYH15_HUMAN (1-685): 8.99e-25: 113: 13.12
+	Mm
		1130947 AKT2_MOUSE (141-523): 4.93e-137: 406: 22.28		GRDN_MOUSE (46-667): 3.61e-15: 82.1: 14.89
+	Hs
		522538 KAPCB_HUMAN (207-524): 1.39e-130: 385: 22.94		MYH1_HUMAN (207-686): 1.24e-21: 102: 12.17
+	Hs
		522610 STK3_HUMAN (224-524): 1.89e-125: 377: 41.25		MYH7_HUMAN (1-566): 2.05e-23: 108: 10.79
+	Hs
		610802 KAPCB_HUMAN (207-524): 1.39e-130: 385: 22.94		MYH4_HUMAN (178-686): 5.68e-21: 100: 6.96
+	Mm
		682109 AKT1_MOUSE (141-523): 6.96e-134: 398: 21.83		GRDN_MOUSE (46-667): 3.61e-15: 82.1: 14.89
+	Hs
		522546 STK3_HUMAN (224-524): 1.89e-125: 377: 41.25		MYH1_HUMAN (207-686): 1.24e-21: 102: 12.17
+	Hs
		681696 AKT1_HUMAN (141-523): 1.99e-133: 397: 21.83		MYH9_HUMAN (311-686): 8.81e-11: 67.7: 10.91
+	Hs
		610795 KAPCB_HUMAN (207-524): 1.39e-130: 385: 22.94		MYH2_HUMAN (325-686): 5.41e-12: 71.5: 12.98
+	Hs
		568568 KAPCA_HUMAN (207-520): 9.62e-131: 385: 22.91		MYH10_HUMAN (350-686): 3.14e-11: 69.2: 11.70
+	Hs
		568567 KAPCA_HUMAN (207-520): 9.62e-131: 385: 22.91		MYH9_HUMAN (311-686): 8.81e-11: 67.7: 10.91
+	Hs
		1027452 STK3_HUMAN (224-524): 1.89e-125: 377: 41.25		MYH2_HUMAN (325-686): 5.41e-12: 71.5: 12.98
+	Hs
		528409 STK3_HUMAN (224-524): 1.89e-125: 377: 41.25		MYH8_HUMAN (350-685): 2.47e-11: 69.6: 10.85
+	Hs
		1027453 STK3_HUMAN (224-524): 1.89e-125: 377: 41.25		MYH13_HUMAN (350-685): 1.78e-09: 63.4: 12.50
+	Hs
		502912 STK3_HUMAN (224-524): 1.89e-125: 377: 41.25		MYH3_HUMAN (350-685): 3.83e-09: 62.3: 12.32
+	Hs
		502911 STK4_HUMAN (221-518): 9.32e-125: 375: 40.00		MYH3_HUMAN (350-685): 3.83e-09: 62.3: 12.32