HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: ZMYM3 (Q14202)
Zinc finger MYM-type protein 3 (Zinc finger protein 261)
Gene: ZMYM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27705803, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 1370
+	Mm
		1322178 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		ZMYM3_MOUSE (1-1370): 0: 2246: 95.12
+	Hs
		800374 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		ZMYM3_HUMAN (1-1370): 0: 2276: 100.00
+	Hs
		949781 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		ZMYM3_HUMAN (1-1370): 0: 2276: 100.00
+	Hs
		1027306 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZMYM2_HUMAN (287-1370): 0: 1483: 43.87
+	Mm
		1321818 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		ZMYM2_MOUSE (287-1370): 0: 1483: 44.18
+	Hs
		949905 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		ZMYM2_HUMAN (287-1370): 0: 1483: 43.87
+	Hs
		1027044 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZMYM4_HUMAN (300-1370): 0: 1422: 39.03
+	Mm
		56876 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		ZMYM4_MOUSE (281-1370): 0: 1419: 38.46
+	Hs
		949810 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		ZMYM4_HUMAN (300-1370): 0: 1422: 39.03
+	Hs
		316061 CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78		ZMYM4_HUMAN (300-1370): 0: 1422: 39.03
+	Dm
		66009 Q9W396_DROME (29-175): 4.55e-52: 168: 56.95		A8JRE3_DROME (310-581): 3.18e-84: 306: 25.99
+	Dm
		66003 Q9VCU6_DROME (25-170): 2.08e-46: 153: 39.46		A8JRE3_DROME (310-581): 3.18e-84: 306: 25.99
+	Dm
		65994 HP1_DROME (9-180): 2.12e-45: 150: 38.73		A8JRE3_DROME (310-581): 3.18e-84: 306: 25.99
+	Hs
		1027036 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZMYM1_HUMAN (537-825): 1.61e-11: 71.4: 16.82