HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 136
+	Hs
		934721 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1027017 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Mm
		952270 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		H32_MOUSE (1-136): 3.73e-61: 186: 100.00
+	Hs
		952310 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Mm
		952771 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		800341 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		800397 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		800347 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		800434 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Mm
		952259 CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89		H32_MOUSE (1-136): 3.73e-61: 186: 100.00
+	Mm
		952749 CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		934657 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Mm
		935445 CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33		H31_MOUSE (1-136): 1.98e-62: 189: 99.27
+	Hs
		828217 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Hs
		949795 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		949755 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		949821 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Mm
		949929 CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33		H32_MOUSE (1-136): 3.73e-61: 186: 100.00
+	Dm
		356124 Q9W396_DROME (29-175): 4.55e-52: 168: 56.95		H3_DROME (1-136): 3.73e-61: 186: 100.00
+	Hs
		800317 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00