HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: HMGX4 (Q9UGU5)
HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)
Gene: HMGXB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 601
+	Mm
		818771 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		SOX2_MOUSE (375-551): 5.31e-32: 128: 16.38
+	Hs
		996646 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		449706 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		HMGB1_HUMAN (388-485): 1.57e-24: 103: 30.00
+	Hs
		643340 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		HMGB2_HUMAN (405-494): 1.76e-22: 97.6: 35.56
+	Mm
		818718 CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89		SOX2_MOUSE (375-551): 5.31e-32: 128: 16.38
+	Hs
		617293 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SP100_HUMAN (388-490): 1.64e-16: 85.3: 30.48
+	Dm
		1363173 Q9VCU6_DROME (25-170): 2.08e-46: 153: 39.46		Q9VUD3_DROME (373-528): 1.32e-36: 146: 19.39
+	Mm
		818693 CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33		SOX2_MOUSE (375-551): 5.31e-32: 128: 16.38
+	Dm
		114467 Q9VCU6_DROME (25-170): 2.08e-46: 153: 39.46		M9PCG2_DROME (373-528): 4.32e-36: 144: 19.39
+	Hs
		1027207 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		175775 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		HMGB3_HUMAN (411-495): 5.79e-12: 67.2: 21.84
+	Hs
		617254 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		SP100_HUMAN (388-490): 1.64e-16: 85.3: 30.48
+	Hs
		617403 V9HWG0_HUMAN (11-182): 1.62e-55: 175: 59.89		SP100_HUMAN (388-490): 1.64e-16: 85.3: 30.48
+	Hs
		123152 CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52		TOX4_HUMAN (339-528): 4.7e-37: 148: 24.76
+	Hs
		617284 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		SP100_HUMAN (388-490): 1.64e-16: 85.3: 30.48
+	Dm
		983581 Q9W396_DROME (29-175): 4.55e-52: 168: 56.95		SSRP1_DROME (409-513): 6.49e-16: 83.4: 23.36
+	Hs
		800501 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Dm
		983577 Q9VCU6_DROME (25-170): 2.08e-46: 153: 39.46		SSRP1_DROME (409-513): 6.49e-16: 83.4: 23.36
+	Hs
		123201 CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52		SOX2_HUMAN (377-551): 5.04e-32: 128: 16.57
+	Dm
		398997 HP1_DROME (9-180): 2.12e-45: 150: 38.73		SSRP1_DROME (409-513): 6.49e-16: 83.4: 23.36