Protein: AP3M1
AP-3 complex subunit mu-1 (AP-3 adaptor complex mu3A subunit) (Adaptor-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin)

Gene: AP3M1
Organism: Homo sapiens
Interactions: 149
UniProt ID: Q9Y2T2

Gene Ontology (top 5):
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005769 - early endosome
GO:0005794 - Golgi apparatus
GO:0006622 - protein targeting to lysosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

158902

AP3D1
AP-3 complex subunit delta-1

5

20

Small-scale

0.919

High

948111

AP3S2
AP-3 complex subunit sigma-2

4

20

Small-scale

0.892

High

126203

AP3B1
AP-3 complex subunit beta-1

3

20

High-throughput

0.855

High

1103505

AP3B2
AP-3 complex subunit beta-2

3

20

High-throughput

0.855

High

1364946

AP3S1
AP-3 complex subunit sigma-1

3

20

High-throughput

0.855

High

922554

AP3M2
AP-3 complex subunit mu-2

2

12

High-throughput

0.811

High

783460

TRI23
E3 ubiquitin-protein ligase TRIM23

2

9

High-throughput

0.783

High

1371482

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

5

High-throughput

0.783

High

700810

DMB
HLA class II histocompatibility antigen, DM beta chain

3

2

High-throughput

0.662

High

1460027

RSP14
Radial spoke head 14 homolog

5

4

High-throughput

0.662

High

1247436

ATRAP
Type-1 angiotensin II receptor-associated protein

3

0

High-throughput

0.646

High

1389819

DTBP1
Dysbindin

3

0

High-throughput

0.638

High

1459046

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

0

High-throughput

0.638

High

1335407

CAMKV
CaM kinase-like vesicle-associated protein

2

1

High-throughput

0.628

High

1462441

S12A4
Solute carrier family 12 member 4

3

0

High-throughput

0.620

High

1123242

DPYL1
Dihydropyrimidinase-related protein 1

3

2

High-throughput

0.616

High

1454572

SI1L2
Signal-induced proliferation-associated 1-like protein 2

3

1

High-throughput

0.616

High

1369326

EDA
Ectodysplasin-A

3

1

High-throughput

0.609

High

872056

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

0

High-throughput

0.602

High

1232151

VASN
Vasorin

2

0

High-throughput

0.602

High

647420

IDS
Iduronate 2-sulfatase

2

0

High-throughput

0.585

High

243342

PRKN
E3 ubiquitin-protein ligase parkin

2

10

High-throughput

0.584

High

218989

TGON2
Trans-Golgi network integral membrane protein 2

2

8

Small-scale

0.584

High

380202

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.575

High

1252090

RN19B
E3 ubiquitin-protein ligase RNF19B

2

9

High-throughput

0.574

High

1490787

E41L3
Band 4.1-like protein 3

2

4

High-throughput

0.574

High

1322286

SPG16
Sperm-associated antigen 16 protein

2

1

High-throughput

0.553

High

1438506

ARNT2
Aryl hydrocarbon receptor nuclear translocator 2

2

1

High-throughput

0.553

High

640337

EPHA1
Ephrin type-A receptor 1

2

9

High-throughput

0.549

High

123882

MYO1C
Unconventional myosin-Ic

1

3

High-throughput

0.536

High

1036704

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

1

High-throughput

0.536

High

1347171

WDR48
WD repeat-containing protein 48

1

5

High-throughput

0.536

High

1420550

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

13

High-throughput

0.523

High

908231

BMX
Cytoplasmic tyrosine-protein kinase BMX

2

6

High-throughput

0.521

High

1314491

SLX4
Structure-specific endonuclease subunit SLX4

2

3

High-throughput

0.521

High

844115

HD
Huntingtin

1

3

High-throughput

0.515

High

320516

TM63A
Mechanosensitive cation channel TMEM63A

1

0

High-throughput

0.513

High

1403380

RUFY1
RUN and FYVE domain-containing protein 1

1

10

Small-scale

0.501

High

688652

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

3

High-throughput

0.489

High

913623

KIF11
Kinesin-like protein KIF11

1

3

High-throughput

0.489

High

959428

RAP1B
Ras-related protein Rap-1b

1

9

High-throughput

0.489

High

1228223

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

1

5

High-throughput

0.489

High

1324888

LRC25
Leucine-rich repeat-containing protein 25

1

2

High-throughput

0.489

High

1325102

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

1

High-throughput

0.489

High

1335087

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.489

High

1433659

E41L1
Band 4.1-like protein 1

1

5

High-throughput

0.489

High

1439240

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

4

High-throughput

0.489

High

1439311

E41L5
Band 4.1-like protein 5

1

6

High-throughput

0.489

High

173587

XPO1
Exportin-1

1

15

High-throughput

0.479

High

364065

EGFR
Epidermal growth factor receptor

1

15

High-throughput

0.479

High

401731

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.479

High

412849

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

908067

VAMP7
Vesicle-associated membrane protein 7

1

3

Small-scale

0.479

High

1095856

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

12

High-throughput

0.479

High

1103811

PLD1
Phospholipase D1

1

2

High-throughput

0.479

High

1151941

RHOH
Rho-related GTP-binding protein RhoH

1

15

High-throughput

0.479

High

1233597

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

1276381

ATG9A
Autophagy-related protein 9A

1

6

High-throughput

0.479

High

1291012

TAXB1
Tax1-binding protein 1

1

8

High-throughput

0.479

High

1312629

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

1

High-throughput

0.479

High

1326466

MINK1
Misshapen-like kinase 1

1

2

High-throughput

0.479

High

1396870

SNX27
Sorting nexin-27

1

1

High-throughput

0.479

High

1397579

CI072
Guanine nucleotide exchange factor C9orf72

1

3

High-throughput

0.479

High

299439

FLOT1
Flotillin-1

1

0

High-throughput

0.458

High

1398986

FRMD6
FERM domain-containing protein 6

1

7

High-throughput

0.457

High

380386

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

3

High-throughput

0.445

High

530624

TAU
Microtubule-associated protein tau

1

9

High-throughput

0.445

High

767382

MERL
Merlin

1

6

High-throughput

0.445

High

1208136

S35D3
Solute carrier family 35 member D3

1

1

High-throughput

0.445

High

1209813

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

7

High-throughput

0.445

High

1348824

S35G2
Solute carrier family 35 member G2

1

1

High-throughput

0.445

High

1121382

TRI14
Tripartite motif-containing protein 14

1

2

High-throughput

0.439

High

291598

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.437

High

294557

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

324242

CE152
Centrosomal protein of 152 kDa

1

3

High-throughput

0.437

High

348231

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

6

High-throughput

0.437

High

376123

RASK
GTPase KRas

1

7

High-throughput

0.437

High

386380

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

7

High-throughput

0.437

High

404559

GCR
Glucocorticoid receptor

1

9

High-throughput

0.437

High

440255

LCK
Tyrosine-protein kinase Lck

1

5

High-throughput

0.437

High

451465

NFM
Neurofilament medium polypeptide

1

11

High-throughput

0.437

High

487900

PARP1
Poly [ADP-ribose] polymerase 1

1

5

High-throughput

0.437

High

590080

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

643154

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

2

High-throughput

0.437

High

696917

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

762071

GRK5
G protein-coupled receptor kinase 5

1

5

High-throughput

0.437

High

769565

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

845870

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.437

High

879641

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.437

High

927622

ATX1
Ataxin-1

1

4

High-throughput

0.437

High

935323

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.437

High

971323

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.437

High

1051086

FAK1
Focal adhesion kinase 1

1

18

High-throughput

0.437

High

1087701

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

2

High-throughput

0.437

High

1133197

LASP1
LIM and SH3 domain protein 1

1

1

Small-scale

0.437

High

1138782

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.437

High

1148409

KS6A1
Ribosomal protein S6 kinase alpha-1

1

6

High-throughput

0.437

High

1194472

LARP7
La-related protein 7

1

3

High-throughput

0.437

High

1229778

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

1249350

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1256182

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

1259589

TBA1A
Tubulin alpha-1A chain

1

8

High-throughput

0.437

High

1276999

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.437

High

1292827

SKAP1
Src kinase-associated phosphoprotein 1

1

8

High-throughput

0.437

High

1293218

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1317057

FAM9A
Protein FAM9A

1

1

High-throughput

0.437

High

1330987

CGAS
Cyclic GMP-AMP synthase

1

3

High-throughput

0.437

High

1353311

PARD3
Partitioning defective 3 homolog

1

2

High-throughput

0.437

High

1368687

KAT6A
Histone acetyltransferase KAT6A

1

2

High-throughput

0.437

High

1385128

MOB3A
MOB kinase activator 3A

1

1

High-throughput

0.437

High

1399128

SCLT1
Sodium channel and clathrin linker 1

1

7

High-throughput

0.437

High

1434282

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.437

High

1438258

RHOF
Rho-related GTP-binding protein RhoF

1

16

High-throughput

0.437

High

1439421

E41LA
Band 4.1-like protein 4A

1

6

High-throughput

0.437

High

1459381

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.437

High

1461922

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.437

High

430538

JUN
Transcription factor Jun

1

6

High-throughput

0.407

High

568190

PLSL
Plastin-2

1

1

High-throughput

0.407

High

787725

SPB5
Serpin B5

1

1

High-throughput

0.407

High

1271286

SV2B
Synaptic vesicle glycoprotein 2B

1

3

High-throughput

0.407

High

1384638

S67A1
Solute carrier family 67 member A1

1

2

High-throughput

0.407

High

1437086

AGO3
Protein argonaute-3

3

0

High-throughput

0.347

High

1191620

RABL6
Rab-like protein 6

3

0

High-throughput

0.345

High

1382795

FERM2
Fermitin family homolog 2

2

0

High-throughput

0.328

High

1458400

I36RA
Interleukin-36 receptor antagonist protein

2

0

High-throughput

0.316

High

1490683

PLAK2
PALM2-AKAP2 fusion protein

2

0

High-throughput

0.288

High

238971

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

0

High-throughput

0.279

Low

613491

VINC
Vinculin

1

0

High-throughput

0.279

Low

754126

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.279

Low

821789

CD79B
B-cell antigen receptor complex-associated protein beta chain

1

0

High-throughput

0.279

Low

847798

SSRB
Translocon-associated protein subunit beta

1

0

High-throughput

0.279

Low

1127538

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1128702

ZN460
Zinc finger protein 460

1

0

High-throughput

0.279

Low

1310747

PHF6
PHD finger protein 6

1

0

High-throughput

0.279

Low

1326161

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.279

Low

1326697

MESH1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

1

0

High-throughput

0.279

Low

1411915

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.279

Low

1490914

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.279

Low

800180

COIL
Coilin

1

0

High-throughput

0.249

Low

880752

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.249

Low

1149403

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.249

Low

1162627

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1179167

TECT1
Tectonic-1

1

0

High-throughput

0.249

Low

1338447

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1397130

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.249

Low

1421233

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.249

Low

1451936

MKS1
Tectonic-like complex member MKS1

1

0

High-throughput

0.249

Low

1400784

MYCT
Proton myo-inositol cotransporter

1

0

High-throughput

0.232

Low

1446626

SEM4B
Semaphorin-4B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025