Interactor 1: KGP2 (Q13237)
cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)
Gene: PRKG2

Interactor 2: MYLK (Q15746)
Myosin light chain kinase, smooth muscle (MLCK) (smMLCK) (EC 2.7.11.18) (Kinase-related protein) (KRP) (Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]
Gene: MYLK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 6547441
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~cNMP_binding, Pkinase~fn3, I-set~Pkinase, Pkinase~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006468 - protein phosphorylation
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 762
Hs

1 1914
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024