HitPredict

Interactor 1: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Interactor 2: KRBX4 (Q5JUW0)
KRAB domain-containing protein 4 (KRAB box domain-containing protein 4)
Gene: KRBOX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	26496610, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 835 Hs			1 171
+	Hs
		846675 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF84_HUMAN (1-170): 1.42e-56: 190: 42.35
+	Hs
		1029422 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN268_HUMAN (2-155): 9.07e-52: 178: 42.86
+	Hs
		299537 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN432_HUMAN (1-163): 1.35e-48: 167: 33.74
+	Hs
		73013 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		B4DU56_HUMAN (30-170): 2.14e-30: 117: 12.84
+	Hs
		563805 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF30_HUMAN (49-170): 1.73e-25: 103: 13.18
+	Hs
		563752 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF26_HUMAN (8-143): 3.32e-21: 91.3: 40.58
+	Hs
		563268 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN708_HUMAN (38-147): 7.92e-21: 90.3: 7.83
+	Hs
		91548 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		E7EV44_HUMAN (8-86): 2.19e-22: 90.1: 59.04
+	Hs
		855883 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN140_HUMAN (41-163): 6.15e-20: 87.2: 10.00
+	Hs
		1029425 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN273_HUMAN (66-170): 1.42e-18: 83.8: 10.91
+	Hs
		563368 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF19_HUMAN (53-170): 2.34e-16: 77.3: 12.80
+	Hs
		66656 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN785_HUMAN (41-148): 8.42e-16: 75.3: 10.00
+	Hs
		1029461 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZKSC8_HUMAN (24-120): 2.36e-11: 63: 7.07
+	Hs
		563760 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN37A_HUMAN (49-143): 1.67e-10: 60.3: 13.40
+	Hs
		988831 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN33B_HUMAN (59-170): 7.34e-10: 58.8: 11.97
+	Hs
		977953 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF92_HUMAN (60-170): 1.43e-09: 57.6: 10.17
+	Hs
		988825 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN33A_HUMAN (110-168): 2.34e-09: 57.2: 14.06
+	Hs
		599069 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF10_HUMAN (71-170): 3.02e-09: 56.8: 8.57
+	Hs
		563251 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF12_HUMAN (70-170): 8.7e-09: 55.3: 9.65
+	Hs
		846615 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF81_HUMAN (105-170): 9.21e-09: 55.3: 9.86