HitPredict

Interactor 1: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Interactor 2: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26318153
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 466 Hs			1 355
+	Hs
		1030438 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		852040 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02
+	Hs
		1048279 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		1030211 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52
+	Hs
		516494 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		453329 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		1031497 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52
+	Hs
		516742 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		1030411 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		MSI2H_HUMAN (21-198): 1.49e-15: 78.3: 26.82
+	Hs
		680445 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		TIA1_HUMAN (176-270): 9.56e-14: 73.6: 18.75
+	Hs
		963512 G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00		TIAR_HUMAN (174-269): 2.98e-13: 72.1: 16.50
+	Hs
		1048071 SAFB1_HUMAN (93-439): 7.61e-35: 140: 12.39		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Dm
		1249158 Q8SYC0_DROME (23-421): 1.53e-51: 180: 12.69		Q9VBQ1_DROME (25-355): 9.19e-51: 180: 26.29
+	Hs
		453703 G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Dm
		995770 Q8SYC0_DROME (23-421): 1.53e-51: 180: 12.69		SQD_DROME (78-264): 4.23e-42: 151: 42.55
+	Sc
		376881 BRE5_YEAST (9-441): 5.6e-45: 166: 15.31		PABP_YEAST (61-266): 4.09e-40: 150: 20.48
+	Zm
		22429 A0A1D6Q2L8_MAIZE (6-437): 3.94e-61: 208: 23.45		A0A1D6I0G1_MAIZE (184-269): 1.37e-14: 76.7: 13.79
+	Dm
		137654 O02374_DROME (331-422): 4.95e-16: 82.4: 19.39		SQD_DROME (78-264): 4.23e-42: 151: 42.55
+	Hs
		453376 SAFB1_HUMAN (93-439): 7.61e-35: 140: 12.39		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		201689 CELF5_HUMAN (200-456): 2.14e-15: 80.1: 10.86		MSI1H_HUMAN (21-180): 2.38e-16: 81: 28.13