Protein: FAM3C
Protein FAM3C (Interleukin-like EMT inducer)

Gene: FAM3C
Organism: Homo sapiens
Interactions: 120
UniProt ID: Q92520

Gene Ontology (top 5):
GO:0005125 - cytokine activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005794 - Golgi apparatus
GO:0006954 - inflammatory response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

520949

HLAC
HLA class I histocompatibility antigen, C alpha chain

3

2

High-throughput

0.667

High

1363574

CLC2D
C-type lectin domain family 2 member D

3

9

High-throughput

0.665

High

1084059

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

3

0

High-throughput

0.638

High

1363572

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

4

4

High-throughput

0.633

High

540593

LAMP1
Lysosome-associated membrane glycoprotein 1

2

2

High-throughput

0.628

High

1363578

A4GCT
Alpha-1,4-N-acetylglucosaminyltransferase

3

1

High-throughput

0.609

High

188952

TMPS2
Transmembrane protease serine 2

2

2

High-throughput

0.606

High

211936

SPIT1
Kunitz-type protease inhibitor 1

2

2

High-throughput

0.606

High

939516

FCGRN
IgG receptor FcRn large subunit p51

2

4

High-throughput

0.606

High

1159616

STX1A
Syntaxin-1A

2

1

High-throughput

0.606

High

1242531

GGT6
Glutathione hydrolase 6

2

1

High-throughput

0.606

High

1363576

CLC4E
C-type lectin domain family 4 member E

2

8

High-throughput

0.606

High

1363560

CHST6
Carbohydrate sulfotransferase 6

2

0

High-throughput

0.602

High

230376

CREB3
Cyclic AMP-responsive element-binding protein 3

2

2

High-throughput

0.590

High

360060

NB5R3
NADH-cytochrome b5 reductase 3

2

0

High-throughput

0.580

High

1004148

CXAR
Coxsackievirus and adenovirus receptor

2

0

High-throughput

0.580

High

1094859

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.580

High

1207572

F209A
Protein FAM209A

2

0

High-throughput

0.580

High

1363550

TM45B
Transmembrane protein 45B

2

0

High-throughput

0.580

High

1363567

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.580

High

1239025

NIPA3
Magnesium transporter NIPA3

2

0

High-throughput

0.576

High

1363551

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

2

High-throughput

0.573

High

631379

RAB5A
Ras-related protein Rab-5A

2

3

High-throughput

0.571

High

1363564

GLP3L
Golgi phosphoprotein 3-like

1

3

Small-scale

0.561

High

1363565

GOLP3
Golgi phosphoprotein 3

1

3

Small-scale

0.561

High

292299

B3GL1
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

2

4

High-throughput

0.558

High

194730

FFAR2
Free fatty acid receptor 2

2

2

High-throughput

0.553

High

335258

CXB5
Gap junction beta-5 protein

2

3

High-throughput

0.553

High

850846

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

2

High-throughput

0.553

High

926816

VMAT1
Chromaffin granule amine transporter

2

1

High-throughput

0.553

High

1254000

CL17A
C-type lectin domain family 17, member A

2

9

High-throughput

0.553

High

1363568

SAR1A
Small COPII coat GTPase SAR1A

2

2

High-throughput

0.553

High

1363571

SCN3B
Sodium channel regulatory subunit beta-3

2

2

High-throughput

0.553

High

1363577

HHLA2
HERV-H LTR-associating protein 2

2

3

High-throughput

0.553

High

1363579

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

2

High-throughput

0.553

High

698954

CALX
Calnexin

1

2

High-throughput

0.536

High

1177177

MICB
MHC class I polypeptide-related sequence B

1

4

High-throughput

0.536

High

1177852

CL12B
C-type lectin domain family 12 member B

1

9

High-throughput

0.536

High

1363580

B3GT5
Beta-1,3-galactosyltransferase 5

1

4

High-throughput

0.536

High

1363582

ST14
Suppressor of tumorigenicity 14 protein

1

2

High-throughput

0.536

High

599218

IL7RA
Interleukin-7 receptor subunit alpha

1

1

High-throughput

0.515

High

888944

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.513

High

1245896

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.513

High

1328578

FA24B
Protein FAM24B

1

0

High-throughput

0.513

High

1363553

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.513

High

1363563

NDST4
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4

1

0

High-throughput

0.513

High

832643

AQP2
Aquaporin-2

1

0

High-throughput

0.493

High

1144342

NECT1
Nectin-1

1

0

High-throughput

0.493

High

1363557

SORT
Sortilin

1

0

High-throughput

0.493

High

701422

5HT1B
5-hydroxytryptamine receptor 1B

1

2

High-throughput

0.489

High

870760

CXA8
Gap junction alpha-8 protein

1

3

High-throughput

0.489

High

1330492

LRC52
Leucine-rich repeat-containing protein 52

1

1

High-throughput

0.489

High

1363549

T106A
Transmembrane protein 106A

1

2

High-throughput

0.489

High

1363558

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

2

High-throughput

0.489

High

218556

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

256938

H2B1K
Histone H2B type 1-K

1

1

High-throughput

0.479

High

633932

ATP4A
Potassium-transporting ATPase alpha chain 1

1

2

Small-scale

0.479

High

980967

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

193434

GPR42
G-protein coupled receptor 42

1

3

High-throughput

0.470

High

1363566

S39A2
Zinc transporter ZIP2

1

11

High-throughput

0.470

High

219417

TNF12
Tumor necrosis factor ligand superfamily member 12

1

0

High-throughput

0.458

High

590926

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.458

High

1251164

ZNT10
Calcium/manganese antiporter SLC30A10

1

3

High-throughput

0.445

High

1323738

S39AB
Zinc transporter ZIP11

1

11

High-throughput

0.445

High

1337887

ZNT7
Zinc transporter 7

1

3

High-throughput

0.445

High

1363584

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

3

High-throughput

0.445

High

386039

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

3

High-throughput

0.439

High

779723

MOT8
Monocarboxylate transporter 8

1

2

High-throughput

0.439

High

418315

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.437

High

1004901

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1254855

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1363569

T106B
Transmembrane protein 106B

1

2

High-throughput

0.437

High

722559

CTR1
High affinity cationic amino acid transporter 1

1

3

High-throughput

0.407

High

1363575

S39AA
Zinc transporter ZIP10

1

11

High-throughput

0.407

High

658529

GLRA2
Glycine receptor subunit alpha-2

3

0

High-throughput

0.347

High

1322251

GNT2A
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase

3

0

High-throughput

0.347

High

1363562

CHST8
Carbohydrate sulfotransferase 8

3

0

High-throughput

0.347

High

1027110

REEP5
Receptor expression-enhancing protein 5

2

0

High-throughput

0.328

High

1142513

PDCD1
Programmed cell death protein 1

2

0

High-throughput

0.328

High

261966

RNH1
Ribonuclease H1

2

0

High-throughput

0.316

High

553367

FCGR1
High affinity immunoglobulin gamma Fc receptor I

2

0

High-throughput

0.316

High

595091

KCNA2
Potassium voltage-gated channel subfamily A member 2

2

0

High-throughput

0.316

High

761161

EVI2B
Protein EVI2B

2

0

High-throughput

0.316

High

1092027

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

2

0

High-throughput

0.316

High

1102428

BIK
Bcl-2-interacting killer

2

0

High-throughput

0.316

High

1186011

SOAT
Sodium-dependent organic anion transporter

2

0

High-throughput

0.316

High

1243003

TMM71
Transmembrane protein 71

2

0

High-throughput

0.316

High

1308643

AHNK2
Protein AHNAK2

2

0

High-throughput

0.316

High

1324834

LRC25
Leucine-rich repeat-containing protein 25

2

0

High-throughput

0.316

High

1329384

TEX29
Testis-expressed protein 29

2

0

High-throughput

0.316

High

1334445

RELL2
RELT-like protein 2

2

0

High-throughput

0.316

High

1352475

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.316

High

1359290

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.316

High

1363554

TMM80
Transmembrane protein 80

2

0

High-throughput

0.316

High

1363555

RMD3
Regulator of microtubule dynamics protein 3

2

0

High-throughput

0.316

High

1363559

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.316

High

1363561

MFF
Mitochondrial fission factor

2

0

High-throughput

0.316

High

1363570

TM248
Transmembrane protein 248

2

0

High-throughput

0.316

High

1363581

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.316

High

1363583

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

0

High-throughput

0.316

High

1306878

INLR1
Interferon lambda receptor 1

1

0

High-throughput

0.279

Low

1316337

AGRG5
Adhesion G-protein coupled receptor G5

1

0

High-throughput

0.279

Low

1363556

SEC62
Translocation protein SEC62

1

0

High-throughput

0.279

Low

951945

SYCY2
Syncytin-2

1

0

High-throughput

0.268

Low

1092067

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

1

0

High-throughput

0.268

Low

1292539

AMGO1
Amphoterin-induced protein 1

1

0

High-throughput

0.268

Low

1348775

FNDC9
Fibronectin type III domain-containing protein 9

1

0

High-throughput

0.268

Low

1363552

T4S18
Transmembrane 4 L6 family member 18

1

0

High-throughput

0.268

Low

552333

ADT3
ADP/ATP translocase 3

1

0

High-throughput

0.249

Low

589282

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696069

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768766

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

947243

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.249

Low

1121130

UBE4A
Ubiquitin conjugation factor E4 A

1

0

Small-scale

0.249

Low

1147548

UBE3C
Ubiquitin-protein ligase E3C

1

0

Small-scale

0.249

Low

1229591

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1339113

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

1363573

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

841224

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.232

Low

1326594

CTL3
Choline transporter-like protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025