Interactor 1: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Interactor 2: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 10608806, 18571408, 30089259, 28508083, 20026654, 20360068, 16858402, 15790808
Identification Methods unspecified method, enzymatic study, pull down, x-ray crystallography, affinity chromatography technology, biochemical, in-gel kinase assay, tandem affinity purification
Interaction Type direct interaction, association, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains FAT~FAT, FAT~FATC, FAT~PI3_PI4_kinase, FATC~PI3_PI4_kinase, PI3_PI4_kinase~PI3_PI4_kinase
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0000425 - pexophagy
GO:0000723 - telomere maintenance
GO:0000724 - double-strand break repair via homologous recombination
GO:0001541 - ovarian follicle development
and 82 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 3056
Hs

1 3056
+ Xl
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Hs
+ Sc
+ Sc
+ Dm
+ Sc
+ At
+ Sp
+ Hs
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024