HitPredict

Interactor 1: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Interactor 2: P2RY8 (Q86VZ1)
P2Y purinoceptor 8 (P2Y8)
Gene: P2RY8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3056 Hs			1 359
+	Hs
		1030922 ATM_HUMAN (1-3056): 0: 3806: 100.00		GPR17_HUMAN (15-331): 1.86e-84: 262: 28.53
+	Hs
		895616 ATM_HUMAN (1-3056): 0: 3806: 100.00		CXCR4_HUMAN (23-308): 3.55e-84: 261: 25.26
+	Hs
		723296 ATM_HUMAN (1-3056): 0: 3806: 100.00		APJ_HUMAN (14-346): 1.38e-68: 221: 22.97
+	Hs
		723037 ATM_HUMAN (1-3056): 0: 3806: 100.00		OPRM_HUMAN (12-356): 5.97e-67: 218: 22.51
+	Hs
		824699 ATM_HUMAN (1-3056): 0: 3806: 100.00		NPY2R_HUMAN (9-348): 4.28e-66: 215: 18.34
+	Hs
		1031594 ATM_HUMAN (1-3056): 0: 3806: 100.00		LPAR4_HUMAN (29-301): 9.42e-49: 169: 36.14
+	Hs
		798422 ATM_HUMAN (1-3056): 0: 3806: 100.00		LPAR6_HUMAN (29-301): 3.51e-39: 144: 32.28
+	Hs
		126587 ATM_HUMAN (1-3056): 0: 3806: 100.00		P2Y10_HUMAN (30-307): 9.64e-30: 118: 34.46
+	Hs
		1030924 ATR_HUMAN (1223-3056): 0: 1214: 20.34		GPR17_HUMAN (15-331): 1.86e-84: 262: 28.53
+	Hs
		723038 ATR_HUMAN (1223-3056): 0: 1214: 20.34		OPRM_HUMAN (12-356): 5.97e-67: 218: 22.51
+	Hs
		787471 MTOR_HUMAN (1846-3055): 0: 843: 16.65		GPR17_HUMAN (15-331): 1.86e-84: 262: 28.53
+	Hs
		787434 MTOR_HUMAN (1846-3055): 0: 843: 16.65		CXCR4_HUMAN (23-308): 3.55e-84: 261: 25.26
+	Hs
		787517 MTOR_HUMAN (1846-3055): 0: 843: 16.65		P2RY8_HUMAN (1-359): 1.75e-78: 246: 100.00
+	Hs
		723279 MTOR_HUMAN (1846-3055): 0: 843: 16.65		APJ_HUMAN (14-346): 1.38e-68: 221: 22.97
+	Hs
		787417 MTOR_HUMAN (1846-3055): 0: 843: 16.65		NPY2R_HUMAN (9-348): 4.28e-66: 215: 18.34
+	Hs
		787488 MTOR_HUMAN (1846-3055): 0: 843: 16.65		P2RY6_HUMAN (26-308): 1.22e-29: 117: 31.33
+	Hs
		787552 MTOR_HUMAN (1846-3055): 0: 843: 16.65		CML1_HUMAN (24-330): 1.18e-25: 107: 27.41
+	Hs
		429015 PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20		ADRB2_HUMAN (4-332): 2.82e-71: 229: 15.88
+	Hs
		666304 PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20		NK3R_HUMAN (4-337): 4.85e-64: 212: 18.61
+	Hs
		126582 PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20		P2Y10_HUMAN (30-307): 9.64e-30: 118: 34.46