HitPredict - High confidence protein-protein interactions

Interactor 1: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Interactor 2: CTIP (Q99708)
DNA endonuclease RBBP8 (EC 3.1.-.-) (CtBP-interacting protein) (CtIP) (Retinoblastoma-binding protein 8) (RBBP-8) (Retinoblastoma-interacting protein and myosin-like) (RIM) (Sporulation in the absence of SPO11 protein 2 homolog) (SAE2)
Gene: RBBP8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Method score

Annotation score

Interaction score

0.82

0.60

0.702

Property	Details
Experiments	10910365, 10608806, 23468639, 22544744
Identification Methods	affinity chromatography technology, pull down, unspecified method, enzymatic study, in-gel kinase assay
Interaction Type	physical association, direct interaction, phosphorylation reaction

Property

Details

Experiments

10910365, 10608806, 23468639, 22544744

Identification Methods

affinity chromatography technology, pull down, unspecified method, enzymatic study, in-gel kinase assay

Interaction Type

physical association, direct interaction, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0035861 - site of double-strand break GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	1

Property

Details

Interacting Pfam domains

Common GO terms

GO:0000724 - double-strand break repair via homologous recombination
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0035861 - site of double-strand break
GO:0043231 - intracellular membrane-bounded organelle

Homologous interactions