HitPredict

Interactor 1: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Interactor 2: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 2229
+	Hs
		1032177 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		1032087 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		EIF3A_HUMAN (962-1409): 3.68e-26: 120: 14.63
+	Hs
		1032139 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Mm
		612554 EIF3I_MOUSE (1-325): 1.41e-92: 279: 99.39		EIF3A_MOUSE (842-1525): 6.47e-14: 80.2: 11.41
+	Dm
		1370295 POC1_DROME (39-323): 1.05e-67: 218: 16.38		Q9VLS7_DROME (949-2220): 1.76e-09: 65.6: 9.45
+	Hs
		903218 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		EIF3A_HUMAN (962-1409): 3.68e-26: 120: 14.63
+	Hs
		1288394 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		793042 LIS1_HUMAN (1-82): 2.95e-21: 95.1: 25.61		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		903450 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Mm
		903669 WDR5_MOUSE (180-325): 1.26e-38: 141: 15.65		KMT2C_MOUSE (68-927): 1.34e-13: 79.5: 11.55
+	Hs
		1264784 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		820867 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Hs
		1288258 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		MINT_HUMAN (296-2220): 2.45e-17: 91.8: 8.49
+	Hs
		1164188 BRWD3_HUMAN (65-317): 2.08e-26: 112: 15.72		NCOR2_HUMAN (251-2219): 1.19e-14: 82.8: 7.59
+	Hs
		1288413 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		NCOR2_HUMAN (251-2219): 1.19e-14: 82.8: 7.59
+	Hs
		1056932 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56
+	Hs
		297832 BRWD3_HUMAN (65-317): 2.08e-26: 112: 15.72		K0754_HUMAN (931-1599): 7.19e-11: 70.2: 11.03
+	Dm
		1370339 FBXW7_DROME (215-324): 1.96e-15: 79.3: 13.39		Q9VLS7_DROME (949-2220): 1.76e-09: 65.6: 9.45
+	Dm
		1363032 Q9VCN9_DROME (6-220): 1.64e-12: 70.1: 25.56		Q9VLS7_DROME (949-2220): 1.76e-09: 65.6: 9.45