HitPredict

Interactor 1: DC1I2 (Q13409)
Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)
Gene: DYNC1I2

Interactor 2: NIN (Q8N4C6)
Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein)
Gene: NIN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	26638075, 28718761, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 638 Hs			1 2090
+	Hs
		148085 DC1I1_HUMAN (1-638): 2.67e-129: 396: 75.04		NIN_HUMAN (1-2090): 0: 617: 100.00
+	Hs
		969581 DC1I2_HUMAN (1-638): 3.3e-143: 432: 100.00		CENPE_HUMAN (1236-2090): 8.51e-24: 112: 11.72
+	Hs
		1033363 DC1I2_HUMAN (1-638): 3.3e-143: 432: 100.00		NINL_HUMAN (1044-2050): 5.99e-09: 63.9: 9.93
+	Hs
		551766 WDR5B_HUMAN (367-626): 3.82e-61: 208: 16.15		DESP_HUMAN (1122-2071): 1.98e-15: 85.1: 11.54
+	Hs
		518846 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		TPR_HUMAN (30-1095): 7.67e-28: 126: 10.73
+	Hs
		1318190 TBL1R_HUMAN (317-624): 4.89e-57: 202: 13.11		NINL_HUMAN (1044-2050): 5.99e-09: 63.9: 9.93
+	Hs
		792973 LIS1_HUMAN (472-631): 9.12e-32: 129: 16.88		CENPE_HUMAN (1236-2090): 8.51e-24: 112: 11.72
+	Mm
		925837 LIS1_MOUSE (472-631): 7.91e-32: 129: 16.88		Q155P7_MOUSE (1-1014): 3.09e-23: 110: 11.69
+	Hs
		903233 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		GOGB1_HUMAN (1228-2090): 3.18e-16: 87.7: 10.60
+	Hs
		551854 NLE1_HUMAN (466-625): 5.77e-36: 143: 14.55		DESP_HUMAN (1122-2071): 1.98e-15: 85.1: 11.54
+	Hs
		903240 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		PLEC_HUMAN (320-1163): 1.13e-15: 86.3: 13.21
+	Hs
		551655 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		DESP_HUMAN (1122-2071): 1.98e-15: 85.1: 11.54
+	Hs
		969591 RBBP7_HUMAN (429-613): 3.4e-25: 110: 17.41		CENPE_HUMAN (1236-2090): 8.51e-24: 112: 11.72
+	Hs
		551632 LIS1_HUMAN (472-631): 9.12e-32: 129: 16.88		DESP_HUMAN (1122-2071): 1.98e-15: 85.1: 11.54
+	Hs
		903399 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		MY18A_HUMAN (1488-2028): 1.65e-10: 69: 18.93
+	Hs
		728492 POC1A_HUMAN (512-624): 4.29e-17: 85.6: 16.81		MYH11_HUMAN (1-942): 4.75e-27: 123: 10.69
+	Hs
		793044 LIS1_HUMAN (472-631): 9.12e-32: 129: 16.88		NINL_HUMAN (1044-2050): 5.99e-09: 63.9: 9.93
+	Dm
		116378 CAF1_DROME (421-613): 1.3e-25: 111: 17.23		M9PI41_DROME (1129-2040): 1.19e-11: 72.9: 18.99
+	Hs
		1083436 RBBP7_HUMAN (429-613): 3.4e-25: 110: 17.41		NINL_HUMAN (1044-2050): 5.99e-09: 63.9: 9.93