Interactor 1: ILK (Q13418)
Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (Beta-integrin-linked kinase) (ILK-1) (ILK-2) (p59ILK)
Gene: ILK

Interactor 2: PARVA (Q9NVD7)
Alpha-parvin (Actopaxin) (CH-ILKBP) (Calponin-like integrin-linked kinase-binding protein) (Matrix-remodeling-associated protein 2)
Gene: PARVA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 26186194, 28514442, 11331308, 33961781, 25416956, 25852190, 16189514, 21516116, 26496610, 22767580, 22441983, 32296183, 35271311, 32707033, 36736316, 23455922, 25502805, 31515488, 12432066, 23877428 and 3 others

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Identification Methods affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation, two hybrid array, anti bait coimmunoprecipitation, bimolecular fluorescence complementation, two hybrid prey pooling approach, validated two hybrid, tandem affinity purification and 1 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~PK_Tyr_Ser-Thr
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0030027 - lamellipodium
GO:0034446 - substrate adhesion-dependent cell spreading
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 452
Hs

1 372
+ Mm
+ Hs
+ Mm
+ Dm
+ Hs
+ Ce

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Last updated: 15 Jul 2024